Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
hcaTConserved hypothetical transmembrane protein; Probable permease involved in the uptake of 3-phenylpropionic acid; Belongs to the major facilitator superfamily. Phenyl propionate permease (PPP) (TC 2.A.1.27) family. (388 aa)    
Predicted Functional Partners:
proC
Pyrroline-5-carboxylate reductase (proC); Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
       0.773
xerD
Integrase/recombinase (xerD); Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.
       0.671
rdgC
Conserved hypothetical protein; May be involved in recombination; Belongs to the RdgC family.
       0.556
HI_1666
Conserved hypothetical protein; Similar to GB:U00096 SP:P75848 PID:1787157 percent identity: 49.73; identified by sequence similarity; putative.
  
     0.487
HI_1625
Predicted coding region HI1625; Hypothetical protein; identified by GeneMark; putative.
  
     0.435
HI_0310
Predicted coding region HI0310; Hypothetical protein; identified by GeneMark; putative.
       0.407
pheA
Chorismate mutase / prephenate dehydratase (pheA); Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.
   
 
  0.406
Your Current Organism:
Haemophilus influenzae
NCBI taxonomy Id: 71421
Other names: H. influenzae Rd KW20, Haemophilus influenzae KW20, Haemophilus influenzae Rd, Haemophilus influenzae Rd KW20
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