Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
HI_0318Conserved hypothetical protein; Similar to SP:P54158 PID:1256620 GB:AL009126 percent identity: 23.78; identified by sequence similarity; putative. (172 aa)    
Predicted Functional Partners:
cmoA
Conserved hypothetical protein; Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).
       0.608
HI_1624
Predicted coding region HI1624; Hypothetical protein; identified by GeneMark; putative.
  
     0.523
aspS
aspartyl-tRNA synthetase (aspS); Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp- AMP and then transferred to the acceptor end of tRNA(Asp). Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
       0.480
HI_1405
Predicted coding region HI1405; Hypothetical protein; identified by GeneMark; putative.
  
     0.470
HI_1369
Conserved hypothetical protein; Similar to SP:P31827 GB:X71917 PID:311346 GB:U00096 PID:1787771 percent identity: 25.46; identified by sequence similarity; putative; To E.coli YddB.
  
     0.458
HI_1217
Transferrin-binding protein, putative; Probable receptor, TonB-dependent.
  
     0.452
nudB
datP pyrophosphohydrolase (ntpA); Catalyzes the hydrolysis of dihydroneopterin triphosphate to dihydroneopterin monophosphate and pyrophosphate. Required for efficient folate biosynthesis. Can also hydrolyze nucleoside triphosphates with a preference for dATP.
       0.448
HI_0974
Predicted coding region HI0974; Hypothetical protein; identified by GeneMark; putative.
  
     0.440
vapB1
Virulence associated protein B (vapB); Antitoxin component of a type II toxin-antitoxin (TA) system. Neutralizes the effect of toxin VapC1 (By similarity).
       0.430
vapC1
Virulence associated protein C, putative; Toxic component of a type II toxin-antitoxin (TA) system. Acts as an RNase, its toxic effect is neutralized by VapB1 antitoxin (By similarity); Belongs to the PINc/VapC protein family.
       0.430
Your Current Organism:
Haemophilus influenzae
NCBI taxonomy Id: 71421
Other names: H. influenzae Rd KW20, Haemophilus influenzae KW20, Haemophilus influenzae Rd, Haemophilus influenzae Rd KW20
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