node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
bioB | efp | HI_1022 | HI_0328 | Biotin synthetase (bioB); Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | Elongation factor P (efp); Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation; Belongs to the elongation factor P family. | 0.403 |
bioB | epmB | HI_1022 | HI_0329 | Biotin synthetase (bioB); Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | Conserved hypothetical protein; With EpmA is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF- P) on 'Lys-34'. EpmB appears to act before EpmA. Displays lysine 2,3- aminomutase activity, producing (R)-beta-lysine from (S)-alpha-lysine (L-lysine) (By similarity); Belongs to the radical SAM superfamily. KamA family. | 0.724 |
bioB | lysA | HI_1022 | HI_0727 | Biotin synthetase (bioB); Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | Diaminopimelate decarboxylase (lysA); Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. | 0.807 |
bioB | lysS | HI_1022 | HI_1211 | Biotin synthetase (bioB); Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | lysyl-tRNA synthetase (lysU); Similar to GB:U14003 GB:J03795 SP:P13030 SP:P14825 GB:M30630 percent identity: 70.38; identified by sequence similarity; putative; Belongs to the class-II aminoacyl-tRNA synthetase family. | 0.515 |
bioB | oapB | HI_1022 | HI_0331 | Biotin synthetase (bioB); Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | Opacity associated protein (oapB); Similar to GB:L42023 SP:P44416 PID:1003553 PID:1222256 PID:595943 percent identity: 100.00; identified by sequence similarity; putative. | 0.499 |
dgkA | oapA | HI_0335 | HI_0330 | Diacylglycerol kinase (dgkA); Recycling of diacylglycerol produced during the turnover of membrane phospholipid. | Opacity associated protein (oapA); Cell envelope protein involved in phase variation, confers opaque colony phenotype; Belongs to the OapA family. | 0.420 |
dgkA | oapB | HI_0335 | HI_0331 | Diacylglycerol kinase (dgkA); Recycling of diacylglycerol produced during the turnover of membrane phospholipid. | Opacity associated protein (oapB); Similar to GB:L42023 SP:P44416 PID:1003553 PID:1222256 PID:595943 percent identity: 100.00; identified by sequence similarity; putative. | 0.533 |
dgkA | recO | HI_0335 | HI_0332 | Diacylglycerol kinase (dgkA); Recycling of diacylglycerol produced during the turnover of membrane phospholipid. | DNA repair protein (recO); Involved in DNA repair and RecF pathway recombination. | 0.651 |
dgkA | relA | HI_0335 | HI_0334 | Diacylglycerol kinase (dgkA); Recycling of diacylglycerol produced during the turnover of membrane phospholipid. | GTP pyrophosphokinase (relA); In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. This enzyme catalyzes the formation of pppGpp which is then hydrolyzed to form ppGpp (By similarity). | 0.756 |
dgkA | rlmD | HI_0335 | HI_0333 | Diacylglycerol kinase (dgkA); Recycling of diacylglycerol produced during the turnover of membrane phospholipid. | RNA methyltransferase, putative; Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily. | 0.534 |
efp | bioB | HI_0328 | HI_1022 | Elongation factor P (efp); Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation; Belongs to the elongation factor P family. | Biotin synthetase (bioB); Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | 0.403 |
efp | epmB | HI_0328 | HI_0329 | Elongation factor P (efp); Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation; Belongs to the elongation factor P family. | Conserved hypothetical protein; With EpmA is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF- P) on 'Lys-34'. EpmB appears to act before EpmA. Displays lysine 2,3- aminomutase activity, producing (R)-beta-lysine from (S)-alpha-lysine (L-lysine) (By similarity); Belongs to the radical SAM superfamily. KamA family. | 0.907 |
efp | lysA | HI_0328 | HI_0727 | Elongation factor P (efp); Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation; Belongs to the elongation factor P family. | Diaminopimelate decarboxylase (lysA); Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. | 0.576 |
efp | lysS | HI_0328 | HI_1211 | Elongation factor P (efp); Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation; Belongs to the elongation factor P family. | lysyl-tRNA synthetase (lysU); Similar to GB:U14003 GB:J03795 SP:P13030 SP:P14825 GB:M30630 percent identity: 70.38; identified by sequence similarity; putative; Belongs to the class-II aminoacyl-tRNA synthetase family. | 0.776 |
efp | oapB | HI_0328 | HI_0331 | Elongation factor P (efp); Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation; Belongs to the elongation factor P family. | Opacity associated protein (oapB); Similar to GB:L42023 SP:P44416 PID:1003553 PID:1222256 PID:595943 percent identity: 100.00; identified by sequence similarity; putative. | 0.621 |
epmB | bioB | HI_0329 | HI_1022 | Conserved hypothetical protein; With EpmA is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF- P) on 'Lys-34'. EpmB appears to act before EpmA. Displays lysine 2,3- aminomutase activity, producing (R)-beta-lysine from (S)-alpha-lysine (L-lysine) (By similarity); Belongs to the radical SAM superfamily. KamA family. | Biotin synthetase (bioB); Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | 0.724 |
epmB | efp | HI_0329 | HI_0328 | Conserved hypothetical protein; With EpmA is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF- P) on 'Lys-34'. EpmB appears to act before EpmA. Displays lysine 2,3- aminomutase activity, producing (R)-beta-lysine from (S)-alpha-lysine (L-lysine) (By similarity); Belongs to the radical SAM superfamily. KamA family. | Elongation factor P (efp); Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation; Belongs to the elongation factor P family. | 0.907 |
epmB | lysA | HI_0329 | HI_0727 | Conserved hypothetical protein; With EpmA is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF- P) on 'Lys-34'. EpmB appears to act before EpmA. Displays lysine 2,3- aminomutase activity, producing (R)-beta-lysine from (S)-alpha-lysine (L-lysine) (By similarity); Belongs to the radical SAM superfamily. KamA family. | Diaminopimelate decarboxylase (lysA); Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. | 0.641 |
epmB | oapA | HI_0329 | HI_0330 | Conserved hypothetical protein; With EpmA is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF- P) on 'Lys-34'. EpmB appears to act before EpmA. Displays lysine 2,3- aminomutase activity, producing (R)-beta-lysine from (S)-alpha-lysine (L-lysine) (By similarity); Belongs to the radical SAM superfamily. KamA family. | Opacity associated protein (oapA); Cell envelope protein involved in phase variation, confers opaque colony phenotype; Belongs to the OapA family. | 0.542 |
epmB | oapB | HI_0329 | HI_0331 | Conserved hypothetical protein; With EpmA is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF- P) on 'Lys-34'. EpmB appears to act before EpmA. Displays lysine 2,3- aminomutase activity, producing (R)-beta-lysine from (S)-alpha-lysine (L-lysine) (By similarity); Belongs to the radical SAM superfamily. KamA family. | Opacity associated protein (oapB); Similar to GB:L42023 SP:P44416 PID:1003553 PID:1222256 PID:595943 percent identity: 100.00; identified by sequence similarity; putative. | 0.586 |