Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
oapBOpacity associated protein (oapB); Similar to GB:L42023 SP:P44416 PID:1003553 PID:1222256 PID:595943 percent identity: 100.00; identified by sequence similarity; putative. (134 aa)    
Predicted Functional Partners:
recO
DNA repair protein (recO); Involved in DNA repair and RecF pathway recombination.
       0.774
rlmD
RNA methyltransferase, putative; Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily.
       0.774
oapA
Opacity associated protein (oapA); Cell envelope protein involved in phase variation, confers opaque colony phenotype; Belongs to the OapA family.
     
 0.745
epmB
Conserved hypothetical protein; With EpmA is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF- P) on 'Lys-34'. EpmB appears to act before EpmA. Displays lysine 2,3- aminomutase activity, producing (R)-beta-lysine from (S)-alpha-lysine (L-lysine) (By similarity); Belongs to the radical SAM superfamily. KamA family.
     
 0.591
relA
GTP pyrophosphokinase (relA); In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. This enzyme catalyzes the formation of pppGpp which is then hydrolyzed to form ppGpp (By similarity).
       0.558
dgkA
Diacylglycerol kinase (dgkA); Recycling of diacylglycerol produced during the turnover of membrane phospholipid.
       0.533
efp
Elongation factor P (efp); Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation; Belongs to the elongation factor P family.
     
 0.447
lppB
Lipoprotein; May be a virulence determinant; Belongs to the E.coli NlpD/Haemophilus LppB family.
      
 0.430
Your Current Organism:
Haemophilus influenzae
NCBI taxonomy Id: 71421
Other names: H. influenzae Rd KW20, Haemophilus influenzae KW20, Haemophilus influenzae Rd, Haemophilus influenzae Rd KW20
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