Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
recODNA repair protein (recO); Involved in DNA repair and RecF pathway recombination. (236 aa)    
Predicted Functional Partners:
recR
Recombination protein (recR); May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.
 
 
 
 0.958
rlmD
RNA methyltransferase, putative; Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily.
     
 0.856
recF
DNA/ATP binding protein (recF); The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity).
    
 
 0.788
oapB
Opacity associated protein (oapB); Similar to GB:L42023 SP:P44416 PID:1003553 PID:1222256 PID:595943 percent identity: 100.00; identified by sequence similarity; putative.
       0.774
recJ
single-stranded-DNA-specific exonuclease (recJ); Single-stranded-DNA-specific exonuclease. Required for many types of recombinational events, although the stringency of the requirement for RecJ appears to vary with the type of recombinational event monitored and the other recombination gene products which are available (By similarity).
 
   
 0.731
polA
DNA polymerase I (polA); In addition to polymerase activity, this DNA polymerase exhibits 3'-5' and 5'-3' exonuclease activity.
     
 0.721
recQ
ATP-dependent DNA helicase (recQ); DNA helicase; Belongs to the helicase family. RecQ subfamily.
      
 0.697
recX
Regulatory protein (recX); Modulates RecA activity; Belongs to the RecX family.
  
  
 0.695
dgkA
Diacylglycerol kinase (dgkA); Recycling of diacylglycerol produced during the turnover of membrane phospholipid.
  
    0.660
ruvC
Crossover junction endodeoxyribonuclease (ruvC); Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity).
     
 0.657
Your Current Organism:
Haemophilus influenzae
NCBI taxonomy Id: 71421
Other names: H. influenzae Rd KW20, Haemophilus influenzae KW20, Haemophilus influenzae Rd, Haemophilus influenzae Rd KW20
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