| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| HI_0338 | dgkA | HI_0338 | HI_0335 | Conserved hypothetical transmembrane protein; Similar to GB:U00096 PID:1787885 percent identity: 42.60; identified by sequence similarity; putative. | Diacylglycerol kinase (dgkA); Recycling of diacylglycerol produced during the turnover of membrane phospholipid. | 0.550 |
| HI_0338 | glnB | HI_0338 | HI_0337 | Conserved hypothetical transmembrane protein; Similar to GB:U00096 PID:1787885 percent identity: 42.60; identified by sequence similarity; putative. | Nitrogen regulatory protein P-II (glnB); P-II indirectly controls the transcription of the glutamine synthetase gene (GlnA). P-II prevents NR-II-catalyzed conversion of NR- I to NR-I-phosphate, the transcriptional activator of GlnA. When P-II is uridylylated to P-II-UMP, these events are reversed. When the ratio of Gln to 2-ketoglutarate decreases, P-II is uridylylated to P-II-UMP, which causes the deadenylation of glutamine synthetase by GlnE, so activating the enzyme (By similarity). | 0.773 |
| HI_0338 | mog | HI_0338 | HI_0336 | Conserved hypothetical transmembrane protein; Similar to GB:U00096 PID:1787885 percent identity: 42.60; identified by sequence similarity; putative. | Molybdopeterin biosynthesis protein (mog); Catalyzes the adenylation of molybdopterin as part of the biosynthesis of the molybdenum-cofactor. | 0.773 |
| dgkA | HI_0338 | HI_0335 | HI_0338 | Diacylglycerol kinase (dgkA); Recycling of diacylglycerol produced during the turnover of membrane phospholipid. | Conserved hypothetical transmembrane protein; Similar to GB:U00096 PID:1787885 percent identity: 42.60; identified by sequence similarity; putative. | 0.550 |
| dgkA | glnB | HI_0335 | HI_0337 | Diacylglycerol kinase (dgkA); Recycling of diacylglycerol produced during the turnover of membrane phospholipid. | Nitrogen regulatory protein P-II (glnB); P-II indirectly controls the transcription of the glutamine synthetase gene (GlnA). P-II prevents NR-II-catalyzed conversion of NR- I to NR-I-phosphate, the transcriptional activator of GlnA. When P-II is uridylylated to P-II-UMP, these events are reversed. When the ratio of Gln to 2-ketoglutarate decreases, P-II is uridylylated to P-II-UMP, which causes the deadenylation of glutamine synthetase by GlnE, so activating the enzyme (By similarity). | 0.550 |
| dgkA | mog | HI_0335 | HI_0336 | Diacylglycerol kinase (dgkA); Recycling of diacylglycerol produced during the turnover of membrane phospholipid. | Molybdopeterin biosynthesis protein (mog); Catalyzes the adenylation of molybdopterin as part of the biosynthesis of the molybdenum-cofactor. | 0.558 |
| glnB | HI_0338 | HI_0337 | HI_0338 | Nitrogen regulatory protein P-II (glnB); P-II indirectly controls the transcription of the glutamine synthetase gene (GlnA). P-II prevents NR-II-catalyzed conversion of NR- I to NR-I-phosphate, the transcriptional activator of GlnA. When P-II is uridylylated to P-II-UMP, these events are reversed. When the ratio of Gln to 2-ketoglutarate decreases, P-II is uridylylated to P-II-UMP, which causes the deadenylation of glutamine synthetase by GlnE, so activating the enzyme (By similarity). | Conserved hypothetical transmembrane protein; Similar to GB:U00096 PID:1787885 percent identity: 42.60; identified by sequence similarity; putative. | 0.773 |
| glnB | dgkA | HI_0337 | HI_0335 | Nitrogen regulatory protein P-II (glnB); P-II indirectly controls the transcription of the glutamine synthetase gene (GlnA). P-II prevents NR-II-catalyzed conversion of NR- I to NR-I-phosphate, the transcriptional activator of GlnA. When P-II is uridylylated to P-II-UMP, these events are reversed. When the ratio of Gln to 2-ketoglutarate decreases, P-II is uridylylated to P-II-UMP, which causes the deadenylation of glutamine synthetase by GlnE, so activating the enzyme (By similarity). | Diacylglycerol kinase (dgkA); Recycling of diacylglycerol produced during the turnover of membrane phospholipid. | 0.550 |
| glnB | mog | HI_0337 | HI_0336 | Nitrogen regulatory protein P-II (glnB); P-II indirectly controls the transcription of the glutamine synthetase gene (GlnA). P-II prevents NR-II-catalyzed conversion of NR- I to NR-I-phosphate, the transcriptional activator of GlnA. When P-II is uridylylated to P-II-UMP, these events are reversed. When the ratio of Gln to 2-ketoglutarate decreases, P-II is uridylylated to P-II-UMP, which causes the deadenylation of glutamine synthetase by GlnE, so activating the enzyme (By similarity). | Molybdopeterin biosynthesis protein (mog); Catalyzes the adenylation of molybdopterin as part of the biosynthesis of the molybdenum-cofactor. | 0.831 |
| moaA | moaC | HI_1676 | HI_1675 | Molybdenum cofactor biosynthesis protein A (moaA); Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. | Molybdenum cofactor biosynthesis protein C (moaC); Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family. | 0.999 |
| moaA | moaD | HI_1676 | HI_1674 | Molybdenum cofactor biosynthesis protein A (moaA); Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. | Molybdopterin converting factor, subunit 1 (moaD); Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin. | 0.938 |
| moaA | moaE | HI_1676 | HI_1673 | Molybdenum cofactor biosynthesis protein A (moaA); Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. | Molybdopterin converting factor, subunit 2 (moaE); Converts molybdopterin precursor Z into molybdopterin. This requires the incorporation of two sulfur atoms into precursor Z to generate a dithiolene group. The sulfur is provided by MoaD (By similarity); Belongs to the MoaE family. | 0.977 |
| moaA | mobA | HI_1676 | HI_0844 | Molybdenum cofactor biosynthesis protein A (moaA); Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. | Molybdopterin-guanine dinucleotide biosynthesis protein (mob); Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor; Belongs to the MobA family. | 0.691 |
| moaA | mobB | HI_1676 | HI_0851 | Molybdenum cofactor biosynthesis protein A (moaA); Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. | Molybdopterin-guanine dinucleotide biosynthesis protein B (mobB); GTP-binding protein that is not required for the biosynthesis of Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor, and not necessary for the formation of active molybdoenzymes using this form of molybdenum cofactor. May act as an adapter protein to achieve the efficient biosynthesis and utilization of MGD. Displays a weak intrinsic GTPase activity (By similarity); Belongs to the MobB family. | 0.447 |
| moaA | moeA | HI_1676 | HI_1448 | Molybdenum cofactor biosynthesis protein A (moaA); Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. | Molybdopterin biosynthesis protein (moeA); Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP; Belongs to the MoeA family. | 0.966 |
| moaA | mog | HI_1676 | HI_0336 | Molybdenum cofactor biosynthesis protein A (moaA); Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. | Molybdopeterin biosynthesis protein (mog); Catalyzes the adenylation of molybdopterin as part of the biosynthesis of the molybdenum-cofactor. | 0.904 |
| moaC | moaA | HI_1675 | HI_1676 | Molybdenum cofactor biosynthesis protein C (moaC); Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family. | Molybdenum cofactor biosynthesis protein A (moaA); Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. | 0.999 |
| moaC | moaD | HI_1675 | HI_1674 | Molybdenum cofactor biosynthesis protein C (moaC); Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family. | Molybdopterin converting factor, subunit 1 (moaD); Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin. | 0.997 |
| moaC | moaE | HI_1675 | HI_1673 | Molybdenum cofactor biosynthesis protein C (moaC); Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family. | Molybdopterin converting factor, subunit 2 (moaE); Converts molybdopterin precursor Z into molybdopterin. This requires the incorporation of two sulfur atoms into precursor Z to generate a dithiolene group. The sulfur is provided by MoaD (By similarity); Belongs to the MoaE family. | 0.999 |
| moaC | mobA | HI_1675 | HI_0844 | Molybdenum cofactor biosynthesis protein C (moaC); Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family. | Molybdopterin-guanine dinucleotide biosynthesis protein (mob); Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor; Belongs to the MobA family. | 0.840 |