Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
HI_0341Conserved hypothetical protein; Similar to SP:P38521 PID:882488 GB:U00096 PID:1789329 percent identity: 55.65; identified by sequence similarity; putative; To E.coli YggL. (114 aa)    
Predicted Functional Partners:
HI_1543
Conserved hypothetical protein; Similar to GB:U00096 SP:P75915 PID:1787272 percent identity: 39.78; identified by sequence similarity; putative; Belongs to the TorD/DmsD family.
  
     0.733
HI_1236
Conserved hypothetical protein; Similar to PID:868023 GB:U00096 PID:1787900 percent identity: 26.52; identified by sequence similarity; putative.
  
     0.730
trpR
Trp operon repressor (trpR); This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon and prevents the initiation of transcription (By similarity).
  
     0.728
matP
Conserved hypothetical protein; Required for spatial organization of the terminus region of the chromosome (Ter macrodomain) during the cell cycle. Prevents early segregation of duplicated Ter macrodomains during cell division. Binds specifically to matS, which is a 13 bp signature motif repeated within the Ter macrodomain.
  
     0.700
HI_0731
Predicted coding region HI0731; Hypothetical protein; identified by GeneMark; putative.
  
     0.676
HI_1582
Conserved hypothetical protein; Similar to PID:1204257 SP:P52008 GB:U00096 PID:1788183 percent identity: 40.56; identified by sequence similarity; putative; To E.coli YecM.
  
     0.669
HI_1724
Conserved hypothetical protein; Similar to SP:P45567 GB:U00096 PID:1786310 percent identity: 38.98; identified by sequence similarity; putative; Belongs to the UPF0231 family.
  
     0.666
HI_0974.1
Conserved hypothetical protein; Similar to SP:P45566 PID:606197 GB:U00096 PID:1789655 percent identity: 46.15; identified by sequence similarity; putative.
  
     0.647
HI_0845
Conserved hypothetical protein; Similar to GB:L19201 SP:P32126 PID:304964 GB:U00096 PID:1790289 percent identity: 65.91; identified by sequence similarity; putative; To E.coli YihD.
  
     0.614
tfoX
DNA transformation protein (tfoX); Required for DNA transformation. Positively regulates genes required for DNA transformation (late competence-specific genes) in association with CRP. Required for expression of the dprABC operon ; Belongs to the TfoX family.
  
     0.607
Your Current Organism:
Haemophilus influenzae
NCBI taxonomy Id: 71421
Other names: H. influenzae Rd KW20, Haemophilus influenzae KW20, Haemophilus influenzae Rd, Haemophilus influenzae Rd KW20
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