STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
napFFerredoxin-type protein (napF); Could be involved in the maturation of NapA, the catalytic subunit of the periplasmic nitrate reductase, before its export into the periplasm; Belongs to the NapF family. (113 aa)    
Predicted Functional Partners:
napD
napD protein (napD); Chaperone for NapA, the catalytic subunit of the periplasmic nitrate reductase. It binds directly and specifically to the twin- arginine signal peptide of NapA, preventing premature interaction with the Tat translocase and premature export.
  
  
 0.979
pta
Phosphate acetyltransferase (pta); Involved in acetate metabolism; In the N-terminal section; belongs to the CobB/CobQ family.
    
 0.960
maeB
Malate oxidoreductase, putative; Similar to GB:U00096 PID:1788806 PID:1799885 PID:1799887 percent identity: 68.69; identified by sequence similarity; putative; In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
    
 0.945
napH
Ferredoxin-type protein (napH); Required for electron transfer from ubiquinol, via NapC, to the periplasmic nitrate reductase NapAB complex.
 
 
 0.917
rnfB
Iron-sulfur cluster binding protein; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
   
 0.913
napG
Ferredoxin-type protein (napG); Required for electron transfer from ubiquinol, via NapC, to the periplasmic nitrate reductase NapAB complex.
 
 
  0.900
rnfC
Conserved hypothetical protein; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.
   
 0.899
napB
Periplasmic nitrate reductase (napB); Electron transfer subunit of the periplasmic nitrate reductase complex NapAB. Receives electrons from the membrane-anchored tetraheme c-type NapC protein and transfers these to NapA subunit, thus allowing electron flow between membrane and periplasm. Essential for periplasmic nitrate reduction with nitrate as the terminal electron acceptor; Belongs to the NapB family.
 
  
 0.888
napC
Cytochrome C-type protein (napC); Mediates electron flow from quinones to the NapAB complex.
 
  
 0.855
torY
Cytochrome C-type protein (yecK); Part of the anaerobic respiratory chain of trimethylamine-N- oxide reductase TorZ. Required for electron transfer to the TorZ terminal enzyme (By similarity).
 
  
 0.852
Your Current Organism:
Haemophilus influenzae
NCBI taxonomy Id: 71421
Other names: H. influenzae Rd KW20, Haemophilus influenzae KW20, Haemophilus influenzae Rd, Haemophilus influenzae Rd KW20
Server load: low (38%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.