Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
napDnapD protein (napD); Chaperone for NapA, the catalytic subunit of the periplasmic nitrate reductase. It binds directly and specifically to the twin- arginine signal peptide of NapA, preventing premature interaction with the Tat translocase and premature export. (93 aa)    
Predicted Functional Partners:
napF
Ferredoxin-type protein (napF); Could be involved in the maturation of NapA, the catalytic subunit of the periplasmic nitrate reductase, before its export into the periplasm; Belongs to the NapF family.
  
  
 0.979
napB
Periplasmic nitrate reductase (napB); Electron transfer subunit of the periplasmic nitrate reductase complex NapAB. Receives electrons from the membrane-anchored tetraheme c-type NapC protein and transfers these to NapA subunit, thus allowing electron flow between membrane and periplasm. Essential for periplasmic nitrate reduction with nitrate as the terminal electron acceptor; Belongs to the NapB family.
  
  
 0.899
napH
Ferredoxin-type protein (napH); Required for electron transfer from ubiquinol, via NapC, to the periplasmic nitrate reductase NapAB complex.
  
  
 0.796
napG
Ferredoxin-type protein (napG); Required for electron transfer from ubiquinol, via NapC, to the periplasmic nitrate reductase NapAB complex.
  
  
 0.785
dmsA
Anaerobic dimethyl sulfoxide reductase, chain A (dmsA); Catalyzes the reduction of dimethyl sulfoxide (DMSO) to dimethyl sulfide (DMS). The terminal DMSO reductase can also use various sulfoxides and N-oxide compounds as terminal electron acceptor in addition to DMSO (By similarity); Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
  
 
 0.759
napC
Cytochrome C-type protein (napC); Mediates electron flow from quinones to the NapAB complex.
  
  
 0.727
torZ
Biotin sulfoxide reductase (bisC); Reduces trimethylamine-N-oxide (TMAO) into trimethylamine; an anaerobic reaction coupled to energy-yielding reactions.
  
 
 0.707
HI_0527
Ferredoxin (fdx-2); Similar to SP:P00208 percent identity: 59.49; identified by sequence similarity; putative.
  
  
 0.424
Your Current Organism:
Haemophilus influenzae
NCBI taxonomy Id: 71421
Other names: H. influenzae Rd KW20, Haemophilus influenzae KW20, Haemophilus influenzae Rd, Haemophilus influenzae Rd KW20
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