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galE protein (Haemophilus influenzae) - STRING interaction network
"galE" - UDP-glucose 4-epimerase in Haemophilus influenzae
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second shell of interactors
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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galEUDP-glucose 4-epimerase; Involved in the metabolism of galactose. Catalyzes the conversion of UDP-galactose (UDP-Gal) to UDP-glucose (UDP-Glc) through a mechanism involving the transient reduction of NAD. By controlling the internal galactose concentration, it may be linked to the biosynthesis of lipopolysaccharide surface molecules, which are important for the pathogenesis of H.influenzae (338 aa)    
Predicted Functional Partners:
galT
Galactose-1-phosphate uridylyltransferase; Similar to SP-P31764 GB-X65934 PID-1573833 percent identity- 99.14; identified by sequence similarity; putative (349 aa)
   
  0.997
galU
UTP--glucose-1-phosphate uridylyltransferase; May play a role in stationary phase survival (295 aa)
 
 
  0.992
galK
Galactokinase; Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P); Belongs to the GHMP kinase family. GalK subfamily (397 aa)
 
 
  0.980
galM
Aldose 1-epimerase; Mutarotase converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity) (340 aa)
   
  0.921
udp
Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity) (259 aa)
         
  0.788
rfaF
ADP-heptose--LPS heptosyltransferase 2; Similar to SP-P37692 PID-466758 GB-U00096 PID-1790050 percent identity- 63.58; identified by sequence similarity; putative (346 aa)
         
  0.714
HI_1364
Uncharacterized HTH-type transcriptional regulator HI_1364; Similar to SP-P37641 PID-466658 GB-U00096 PID-1789938 percent identity- 36.04; identified by sequence similarity; putative (288 aa)
           
  0.667
hldE
Bifunctional protein HldE; Catalyzes the phosphorylation of D-glycero-D-manno- heptose 7-phosphate at the C-1 position to selectively form D- glycero-beta-D-manno-heptose-1,7-bisphosphate; In the N-terminal section; belongs to the carbohydrate kinase PfkB family (476 aa)
   
   
  0.652
purL
Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate (1320 aa)
         
  0.651
galR
HTH-type transcriptional regulator GalR; Repressor of the galactose operon. Binds galactose as an inducer (332 aa)
     
 
  0.650
Your Current Organism:
Haemophilus influenzae
NCBI taxonomy Id: 71421
Other names: H. influenzae Rd KW20, Haemophilus influenzae, Haemophilus influenzae KW20, Haemophilus influenzae Rd, Haemophilus influenzae Rd KW20
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