| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| HI_0395 | HI_0396 | HI_0395 | HI_0396 | Conserved hypothetical protein; Similar to PID:1033114 SP:P52119 GB:U00096 PID:1788971 percent identity: 55.32; identified by sequence similarity; putative; Belongs to the UPF0125 (RnfH) family. | Conserved hypothetical protein; Oxygenase that catalyzes the hydroxylation of a ribosomal protein; Belongs to the ROX family. | 0.824 |
| HI_0395 | pth | HI_0395 | HI_0394 | Conserved hypothetical protein; Similar to PID:1033114 SP:P52119 GB:U00096 PID:1788971 percent identity: 55.32; identified by sequence similarity; putative; Belongs to the UPF0125 (RnfH) family. | peptidyl-tRNA hydrolase (pth); The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family. | 0.548 |
| HI_0395 | xseA | HI_0395 | HI_0397 | Conserved hypothetical protein; Similar to PID:1033114 SP:P52119 GB:U00096 PID:1788971 percent identity: 55.32; identified by sequence similarity; putative; Belongs to the UPF0125 (RnfH) family. | Exodeoxyribonuclease VII, large subunit (xseA); Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family. | 0.804 |
| HI_0396 | HI_0395 | HI_0396 | HI_0395 | Conserved hypothetical protein; Oxygenase that catalyzes the hydroxylation of a ribosomal protein; Belongs to the ROX family. | Conserved hypothetical protein; Similar to PID:1033114 SP:P52119 GB:U00096 PID:1788971 percent identity: 55.32; identified by sequence similarity; putative; Belongs to the UPF0125 (RnfH) family. | 0.824 |
| HI_0396 | pth | HI_0396 | HI_0394 | Conserved hypothetical protein; Oxygenase that catalyzes the hydroxylation of a ribosomal protein; Belongs to the ROX family. | peptidyl-tRNA hydrolase (pth); The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family. | 0.521 |
| HI_0396 | xseA | HI_0396 | HI_0397 | Conserved hypothetical protein; Oxygenase that catalyzes the hydroxylation of a ribosomal protein; Belongs to the ROX family. | Exodeoxyribonuclease VII, large subunit (xseA); Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family. | 0.808 |
| ispG | xseA | HI_0368 | HI_0397 | gcpE protein (gcpE); Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. | Exodeoxyribonuclease VII, large subunit (xseA); Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family. | 0.564 |
| mutL | recG | HI_0067 | HI_1740 | DNA mismatch repair protein (mutL); This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity). | ATP-dependent DNA helicase (recG); Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA) (By similarity); Belongs to the helicase family. RecG subfamily. | 0.569 |
| mutL | recJ | HI_0067 | HI_1214 | DNA mismatch repair protein (mutL); This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity). | single-stranded-DNA-specific exonuclease (recJ); Single-stranded-DNA-specific exonuclease. Required for many types of recombinational events, although the stringency of the requirement for RecJ appears to vary with the type of recombinational event monitored and the other recombination gene products which are available (By similarity). | 0.793 |
| mutL | recN | HI_0067 | HI_0070 | DNA mismatch repair protein (mutL); This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity). | DNA repair protein (recN); May be involved in recombinational repair of damaged DNA. | 0.585 |
| mutL | ruvA | HI_0067 | HI_0313 | DNA mismatch repair protein (mutL); This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity). | Holliday junction DNA helicase (ruvA); The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. | 0.517 |
| mutL | xseA | HI_0067 | HI_0397 | DNA mismatch repair protein (mutL); This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity). | Exodeoxyribonuclease VII, large subunit (xseA); Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family. | 0.547 |
| mutL | xseB | HI_0067 | HI_1437 | DNA mismatch repair protein (mutL); This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity). | Exodeoxyribonuclease, small subunit (xseB); Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides. It can also degrade 3' or 5' ss regions extending from the termini of duplex DNA molecules and displaced ss regions (By similarity); Belongs to the XseB family. | 0.467 |
| pth | HI_0395 | HI_0394 | HI_0395 | peptidyl-tRNA hydrolase (pth); The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family. | Conserved hypothetical protein; Similar to PID:1033114 SP:P52119 GB:U00096 PID:1788971 percent identity: 55.32; identified by sequence similarity; putative; Belongs to the UPF0125 (RnfH) family. | 0.548 |
| pth | HI_0396 | HI_0394 | HI_0396 | peptidyl-tRNA hydrolase (pth); The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family. | Conserved hypothetical protein; Oxygenase that catalyzes the hydroxylation of a ribosomal protein; Belongs to the ROX family. | 0.521 |
| pth | xseA | HI_0394 | HI_0397 | peptidyl-tRNA hydrolase (pth); The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family. | Exodeoxyribonuclease VII, large subunit (xseA); Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family. | 0.546 |
| recG | mutL | HI_1740 | HI_0067 | ATP-dependent DNA helicase (recG); Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA) (By similarity); Belongs to the helicase family. RecG subfamily. | DNA mismatch repair protein (mutL); This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity). | 0.569 |
| recG | recJ | HI_1740 | HI_1214 | ATP-dependent DNA helicase (recG); Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA) (By similarity); Belongs to the helicase family. RecG subfamily. | single-stranded-DNA-specific exonuclease (recJ); Single-stranded-DNA-specific exonuclease. Required for many types of recombinational events, although the stringency of the requirement for RecJ appears to vary with the type of recombinational event monitored and the other recombination gene products which are available (By similarity). | 0.716 |
| recG | recN | HI_1740 | HI_0070 | ATP-dependent DNA helicase (recG); Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA) (By similarity); Belongs to the helicase family. RecG subfamily. | DNA repair protein (recN); May be involved in recombinational repair of damaged DNA. | 0.643 |
| recG | ruvA | HI_1740 | HI_0313 | ATP-dependent DNA helicase (recG); Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA) (By similarity); Belongs to the helicase family. RecG subfamily. | Holliday junction DNA helicase (ruvA); The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. | 0.725 |
