Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
HI_0400Conserved hypothetical protein; Similar to GB:U00096 PID:1788685 percent identity: 42.42; identified by sequence similarity; putative; Belongs to the UPF0381 family. (95 aa)    
Predicted Functional Partners:
HI_0974.1
Conserved hypothetical protein; Similar to SP:P45566 PID:606197 GB:U00096 PID:1789655 percent identity: 46.15; identified by sequence similarity; putative.
  
     0.771
HI_0845
Conserved hypothetical protein; Similar to GB:L19201 SP:P32126 PID:304964 GB:U00096 PID:1790289 percent identity: 65.91; identified by sequence similarity; putative; To E.coli YihD.
  
     0.755
lapA
Conserved hypothetical protein; Involved in the assembly of lipopolysaccharide (LPS). Belongs to the LapA family.
  
     0.751
arfA
Conserved hypothetical protein; Rescues ribosomes stalled at the 3' end of non-stop mRNAs. Recruits release factor 2 (RF2) to the stalled ribosome, helping position it correctly in the ribosomal A site so its GGQ motif can hydrolyze the peptidyl-tRNA bond (By similarity).
  
     0.750
holD
DNA polymerase III, psi subunit (holD); DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is unknown (By similarity).
  
     0.738
HI_0162
Lipoprotein, putative; Similar to GB:U00096 PID:1773118 PID:1786637 percent identity: 25.82; identified by sequence similarity; putative.
  
     0.722
HI_1168
Conserved hypothetical protein; Similar to GB:U00096 PID:1788317 percent identity: 56.14; identified by sequence similarity; putative; Belongs to the UPF0265 family.
  
    0.716
mukF
Killing protein (kicB); Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity.
  
     0.714
HI_0866
Predicted coding region HI0866; Hypothetical protein; identified by GeneMark; putative.
  
     0.713
hemY
hemY protein (hemY); Involved in a late step of protoheme IX synthesis.
  
     0.703
Your Current Organism:
Haemophilus influenzae
NCBI taxonomy Id: 71421
Other names: H. influenzae Rd KW20, Haemophilus influenzae KW20, Haemophilus influenzae Rd, Haemophilus influenzae Rd KW20
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