STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
comECompetence protein E (comE); Involved in transformation (competence for DNA uptake); Belongs to the bacterial secretin family. PilQ subfamily. (445 aa)    
Predicted Functional Partners:
comB
Competence protein B (comB); Involved in transformation (competence for DNA uptake).
  
 
 0.987
comA
Competence protein A (comA); Involved in transformation (competence for DNA uptake).
  
 
 0.927
hofC
Protein transport protein; Similar to GB:M32066 SP:P22609 PID:151066 percent identity: 29.18; identified by sequence similarity; putative.
 
 
 
 0.924
hofB
Protein transport protein; Similar to GB:M32066 SP:P22608 GB:S43866 PID:151065 percent identity: 41.16; identified by sequence similarity; putative; Belongs to the GSP E family.
 
 
 
 0.920
comD
Competence protein D (comD); Involved in transformation (competence for DNA uptake).
     
 0.917
comF
Competence protein F (comF); Involved in transformation (competence for DNA uptake).
     
 0.875
comC
Competence protein C (comC); Involved in transformation (competence for DNA uptake).
       0.807
ppdD
Prepilin peptidase dependent protein D; Similar to GB:D26562 SP:P36647 GB:L28105 PID:473777 PID:456042 percent identity: 41.54; identified by sequence similarity; putative.
 
   
 0.804
mrcA
Penicillin-binding protein 1A (ponA); Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits).
     
 0.693
rec2
Recombination protein (rec2); Might contribute to transformation as a member of a membrane- bound pore complex at the base of the transformasome. It could directly interact with transforming DNA during translocation indirectly by participating in the assembly of the pore.
      
 0.672
Your Current Organism:
Haemophilus influenzae
NCBI taxonomy Id: 71421
Other names: H. influenzae Rd KW20, Haemophilus influenzae KW20, Haemophilus influenzae Rd, Haemophilus influenzae Rd KW20
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.