comA protein (Haemophilus influenzae) - STRING interaction network

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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[Homology]

Score

comA

Competence protein A (comA); Involved in transformation (competence for DNA uptake). (265 aa)

Predicted Functional Partners:

comB

0.987

comE

0.927

comD

0.808

comF

0.794

comC

0.775

hofC

0.592

hofB

0.592

mrcA

0.581

nfuA

0.564

rec2

0.518

Your Current Organism:

Haemophilus influenzae

NCBI taxonomy Id: 71421
Other names: H. influenzae Rd KW20, Haemophilus influenzae KW20, Haemophilus influenzae Rd, Haemophilus influenzae Rd KW20

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
comA	comB	HI_0439	HI_0438	Competence protein A (comA); Involved in transformation (competence for DNA uptake).	Competence protein B (comB); Involved in transformation (competence for DNA uptake).	0.987
comA	comC	HI_0439	HI_0437	Competence protein A (comA); Involved in transformation (competence for DNA uptake).	Competence protein C (comC); Involved in transformation (competence for DNA uptake).	0.775
comA	comD	HI_0439	HI_0436	Competence protein A (comA); Involved in transformation (competence for DNA uptake).	Competence protein D (comD); Involved in transformation (competence for DNA uptake).	0.808
comA	comE	HI_0439	HI_0435	Competence protein A (comA); Involved in transformation (competence for DNA uptake).	Competence protein E (comE); Involved in transformation (competence for DNA uptake); Belongs to the bacterial secretin family. PilQ subfamily.	0.927
comA	comF	HI_0439	HI_0434	Competence protein A (comA); Involved in transformation (competence for DNA uptake).	Competence protein F (comF); Involved in transformation (competence for DNA uptake).	0.794
comA	hofB	HI_0439	HI_0298	Competence protein A (comA); Involved in transformation (competence for DNA uptake).	Protein transport protein; Similar to GB:M32066 SP:P22608 GB:S43866 PID:151065 percent identity: 41.16; identified by sequence similarity; putative; Belongs to the GSP E family.	0.592
comA	hofC	HI_0439	HI_0297	Competence protein A (comA); Involved in transformation (competence for DNA uptake).	Protein transport protein; Similar to GB:M32066 SP:P22609 PID:151066 percent identity: 29.18; identified by sequence similarity; putative.	0.592
comA	mrcA	HI_0439	HI_0440	Competence protein A (comA); Involved in transformation (competence for DNA uptake).	Penicillin-binding protein 1A (ponA); Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits).	0.581
comA	nfuA	HI_0439	HI_0433	Competence protein A (comA); Involved in transformation (competence for DNA uptake).	orfG protein; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins.	0.564
comA	rec2	HI_0439	HI_0061	Competence protein A (comA); Involved in transformation (competence for DNA uptake).	Recombination protein (rec2); Might contribute to transformation as a member of a membrane- bound pore complex at the base of the transformasome. It could directly interact with transforming DNA during translocation indirectly by participating in the assembly of the pore.	0.518
comB	comA	HI_0438	HI_0439	Competence protein B (comB); Involved in transformation (competence for DNA uptake).	Competence protein A (comA); Involved in transformation (competence for DNA uptake).	0.987
comB	comC	HI_0438	HI_0437	Competence protein B (comB); Involved in transformation (competence for DNA uptake).	Competence protein C (comC); Involved in transformation (competence for DNA uptake).	0.807
comB	comD	HI_0438	HI_0436	Competence protein B (comB); Involved in transformation (competence for DNA uptake).	Competence protein D (comD); Involved in transformation (competence for DNA uptake).	0.913
comB	comE	HI_0438	HI_0435	Competence protein B (comB); Involved in transformation (competence for DNA uptake).	Competence protein E (comE); Involved in transformation (competence for DNA uptake); Belongs to the bacterial secretin family. PilQ subfamily.	0.987
comB	comF	HI_0438	HI_0434	Competence protein B (comB); Involved in transformation (competence for DNA uptake).	Competence protein F (comF); Involved in transformation (competence for DNA uptake).	0.852
comB	hofB	HI_0438	HI_0298	Competence protein B (comB); Involved in transformation (competence for DNA uptake).	Protein transport protein; Similar to GB:M32066 SP:P22608 GB:S43866 PID:151065 percent identity: 41.16; identified by sequence similarity; putative; Belongs to the GSP E family.	0.729
comB	hofC	HI_0438	HI_0297	Competence protein B (comB); Involved in transformation (competence for DNA uptake).	Protein transport protein; Similar to GB:M32066 SP:P22609 PID:151066 percent identity: 29.18; identified by sequence similarity; putative.	0.592
comB	mrcA	HI_0438	HI_0440	Competence protein B (comB); Involved in transformation (competence for DNA uptake).	Penicillin-binding protein 1A (ponA); Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits).	0.574
comB	nfuA	HI_0438	HI_0433	Competence protein B (comB); Involved in transformation (competence for DNA uptake).	orfG protein; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins.	0.564
comB	rec2	HI_0438	HI_0061	Competence protein B (comB); Involved in transformation (competence for DNA uptake).	Recombination protein (rec2); Might contribute to transformation as a member of a membrane- bound pore complex at the base of the transformasome. It could directly interact with transforming DNA during translocation indirectly by participating in the assembly of the pore.	0.665