Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
vapDVirulence associated protein D (vapD); Cleaves ssRNA, mostly between U:A; Belongs to the VapD ribonuclease family. (91 aa)    
Predicted Functional Partners:
HI_0451
Conserved hypothetical protein; Similar to PID:1196479 percent identity: 56.67; identified by sequence similarity; putative.
   
 
 0.986
HI_0452
Conserved hypothetical protein; Similar to GB:U14003 SP:P39319 PID:537059 GB:U00096 PID:1790664 percent identity: 52.57; identified by sequence similarity; putative.
     
 0.686
HI_0449
Predicted coding region HI0449; Hypothetical protein; identified by GeneMark; putative.
       0.547
HI_1250
Predicted coding region HI1250; Hypothetical protein; identified by GeneMark; putative.
      
 0.466
HI_0453
Conserved hypothetical protein; Similar to GB:AE000511 PID:2313105 percent identity: 41.52; identified by sequence similarity; putative.
       0.465
tmk
Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.
     
 0.461
yafQ
Conserved hypothetical protein; Toxic component of a type II toxin-antitoxin (TA) system. Its cognate antitoxin is RelB (By similarity).
      
 0.444
HI_0454
Conserved hypothetical protein; Similar to SP:P37346 GB:U00096 PID:1787342 percent identity: 59.92; identified by sequence similarity; putative.
       0.424
fruA
PTS system, fructose-specific IIBC component (fruA); The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II FruAB PTS system is involved in fructose transport.
       0.417
fruK
1-phosphofructokinase (fruK); Similar to SP:P23539 GB:X53948 PID:405894 PID:41487 GB:U00096 percent identity: 55.41; identified by sequence similarity; putative; Belongs to the carbohydrate kinase PfkB family.
       0.417
Your Current Organism:
Haemophilus influenzae
NCBI taxonomy Id: 71421
Other names: H. influenzae Rd KW20, Haemophilus influenzae KW20, Haemophilus influenzae Rd, Haemophilus influenzae Rd KW20
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