Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
Experiments
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[Homology]
Score
HI_0454Conserved hypothetical protein; Similar to SP:P37346 GB:U00096 PID:1787342 percent identity: 59.92; identified by sequence similarity; putative. (260 aa)    
Predicted Functional Partners:
mltG
Conserved hypothetical protein; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. Belongs to the transglycosylase MltG family.
      0.899
HI_0453
Conserved hypothetical protein; Similar to GB:AE000511 PID:2313105 percent identity: 41.52; identified by sequence similarity; putative.
       0.730
holB
DNA polymerase III, delta' subunit (holB); DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity).
  
  
 0.690
tmk
Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.
     
 0.678
HI_0452
Conserved hypothetical protein; Similar to GB:U14003 SP:P39319 PID:537059 GB:U00096 PID:1790664 percent identity: 52.57; identified by sequence similarity; putative.
       0.558
tatC
Conserved hypothetical protein; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
     
 0.536
surA
Stationary phase survival protein SurA, putative; Chaperone involved in the folding of extracytoplasmic proteins.
       0.522
dnaX
DNA polymerase III, subunits gamma and tau (dnaX); DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity; Belongs to the DnaX/STICHEL family.
 
   
 0.447
vapD
Virulence associated protein D (vapD); Cleaves ssRNA, mostly between U:A; Belongs to the VapD ribonuclease family.
       0.424
HI_0451
Conserved hypothetical protein; Similar to PID:1196479 percent identity: 56.67; identified by sequence similarity; putative.
       0.424
Your Current Organism:
Haemophilus influenzae
NCBI taxonomy Id: 71421
Other names: H. influenzae Rd KW20, Haemophilus influenzae KW20, Haemophilus influenzae Rd, Haemophilus influenzae Rd KW20
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