Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
HI_0467Conserved hypothetical protein; Similar to GB:L10328 SP:P23839 GB:X14235 PID:290494 PID:42721 percent identity: 64.81; identified by sequence similarity; putative; Belongs to the UPF0701 family. (287 aa)    
Predicted Functional Partners:
HI_0466
Conserved hypothetical protein; Similar to PID:887848 GB:U00096 SP:P39179 PID:1789265 percent identity: 40.36; identified by sequence similarity; putative; To E.coli YgfZ (UP14) and B.aphidicola (subsp. Acyrthosiphon pisum) BU435.
       0.832
gmk
Guanylate kinase (gmk); Essential for recycling GMP and indirectly, cGMP.
  
    0.567
rpoZ
DNA-directed RNA polymerase, omega chain (rpoZ); Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity).
  
  
 0.423
Your Current Organism:
Haemophilus influenzae
NCBI taxonomy Id: 71421
Other names: H. influenzae Rd KW20, Haemophilus influenzae KW20, Haemophilus influenzae Rd, Haemophilus influenzae Rd KW20
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