STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
hindIIRType II restriction endonuclease (HindIIR); Recognizes the double-stranded sequence GTYRAC and cleaves after Y-3. (258 aa)    
Predicted Functional Partners:
hindIIM
Modification methylase (hindIIM); This methylase recognizes the double-stranded sequence GTYRAC, causes specific methylation on A-5 on both strands, and protects the DNA from cleavage by the HindII endonuclease; Belongs to the N(4)/N(6)-methyltransferase family.
       0.773
hindIIIR
Type II restriction endonuclease (hindIIIR); Recognizes the double-stranded sequence AAGCTT and cleaves after A-1.
      
 0.618
hindVRP
Type II restriction enzyme, putative; Similar to SP:P25261 SP:P24599 PID:43474 percent identity: 43.56; identified by sequence similarity; putative.
      
 0.588
hindVM
Modification methylase; This methylase recognizes the double-stranded sequence GRCGYC, causes specific methylation on C-? on both strands, and protects the DNA from cleavage by the HindV endonuclease; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
      
 0.588
rpoC
DNA-directed RNA polymerase, beta' chain (rpoC); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
       0.570
tehA
Tellurite resistance protein (tehA); Ion channel involved in potassium tellurite resistance. Belongs to the tellurite-resistance/dicarboxylate transporter (TDT) family.
       0.437
Your Current Organism:
Haemophilus influenzae
NCBI taxonomy Id: 71421
Other names: H. influenzae Rd KW20, Haemophilus influenzae KW20, Haemophilus influenzae Rd, Haemophilus influenzae Rd KW20
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