node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
HI_0304 | hindIIM | HI_0304 | HI_0513 | Conserved hypothetical protein; Similar to PID:882477 SP:P52049 GB:U00096 PID:1789317 percent identity: 44.57; identified by sequence similarity; putative; Belongs to the UPF0301 (AlgH) family. | Modification methylase (hindIIM); This methylase recognizes the double-stranded sequence GTYRAC, causes specific methylation on A-5 on both strands, and protects the DNA from cleavage by the HindII endonuclease; Belongs to the N(4)/N(6)-methyltransferase family. | 0.424 |
HI_0304 | nadR | HI_0304 | HI_0763 | Conserved hypothetical protein; Similar to PID:882477 SP:P52049 GB:U00096 PID:1789317 percent identity: 44.57; identified by sequence similarity; putative; Belongs to the UPF0301 (AlgH) family. | Transcriptional regulator (nadR); This enzyme has two activities: nicotinamide mononucleotide (NMN) adenylyltransferase and ribosylnicotinamide (RN) kinase. The RN kinase activity catalyzes the phosphorylation of RN to form nicotinamide ribonucleotide. The NMN adenylyltransferase activity catalyzes the transfer of the AMP moiety of ATP to nicotinamide ribonucleotide to form NAD(+); In the C-terminal section; belongs to the bacterial RNK family. | 0.936 |
hindIIM | HI_0304 | HI_0513 | HI_0304 | Modification methylase (hindIIM); This methylase recognizes the double-stranded sequence GTYRAC, causes specific methylation on A-5 on both strands, and protects the DNA from cleavage by the HindII endonuclease; Belongs to the N(4)/N(6)-methyltransferase family. | Conserved hypothetical protein; Similar to PID:882477 SP:P52049 GB:U00096 PID:1789317 percent identity: 44.57; identified by sequence similarity; putative; Belongs to the UPF0301 (AlgH) family. | 0.424 |
hindIIM | hindIIR | HI_0513 | HI_0512 | Modification methylase (hindIIM); This methylase recognizes the double-stranded sequence GTYRAC, causes specific methylation on A-5 on both strands, and protects the DNA from cleavage by the HindII endonuclease; Belongs to the N(4)/N(6)-methyltransferase family. | Type II restriction endonuclease (HindIIR); Recognizes the double-stranded sequence GTYRAC and cleaves after Y-3. | 0.773 |
hindIIM | mtnN | HI_0513 | HI_1216 | Modification methylase (hindIIM); This methylase recognizes the double-stranded sequence GTYRAC, causes specific methylation on A-5 on both strands, and protects the DNA from cleavage by the HindII endonuclease; Belongs to the N(4)/N(6)-methyltransferase family. | Pfs protein (pfs); Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Belongs to the PNP/UDP phosphorylase family. MtnN subfamily. | 0.571 |
hindIIM | nadR | HI_0513 | HI_0763 | Modification methylase (hindIIM); This methylase recognizes the double-stranded sequence GTYRAC, causes specific methylation on A-5 on both strands, and protects the DNA from cleavage by the HindII endonuclease; Belongs to the N(4)/N(6)-methyltransferase family. | Transcriptional regulator (nadR); This enzyme has two activities: nicotinamide mononucleotide (NMN) adenylyltransferase and ribosylnicotinamide (RN) kinase. The RN kinase activity catalyzes the phosphorylation of RN to form nicotinamide ribonucleotide. The NMN adenylyltransferase activity catalyzes the transfer of the AMP moiety of ATP to nicotinamide ribonucleotide to form NAD(+); In the C-terminal section; belongs to the bacterial RNK family. | 0.968 |
hindIIM | rpoC | HI_0513 | HI_0514 | Modification methylase (hindIIM); This methylase recognizes the double-stranded sequence GTYRAC, causes specific methylation on A-5 on both strands, and protects the DNA from cleavage by the HindII endonuclease; Belongs to the N(4)/N(6)-methyltransferase family. | DNA-directed RNA polymerase, beta' chain (rpoC); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.602 |
hindIIM | tehA | HI_0513 | HI_0511 | Modification methylase (hindIIM); This methylase recognizes the double-stranded sequence GTYRAC, causes specific methylation on A-5 on both strands, and protects the DNA from cleavage by the HindII endonuclease; Belongs to the N(4)/N(6)-methyltransferase family. | Tellurite resistance protein (tehA); Ion channel involved in potassium tellurite resistance. Belongs to the tellurite-resistance/dicarboxylate transporter (TDT) family. | 0.437 |
hindIIR | hindIIM | HI_0512 | HI_0513 | Type II restriction endonuclease (HindIIR); Recognizes the double-stranded sequence GTYRAC and cleaves after Y-3. | Modification methylase (hindIIM); This methylase recognizes the double-stranded sequence GTYRAC, causes specific methylation on A-5 on both strands, and protects the DNA from cleavage by the HindII endonuclease; Belongs to the N(4)/N(6)-methyltransferase family. | 0.773 |
hindIIR | rpoC | HI_0512 | HI_0514 | Type II restriction endonuclease (HindIIR); Recognizes the double-stranded sequence GTYRAC and cleaves after Y-3. | DNA-directed RNA polymerase, beta' chain (rpoC); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.570 |
hindIIR | tehA | HI_0512 | HI_0511 | Type II restriction endonuclease (HindIIR); Recognizes the double-stranded sequence GTYRAC and cleaves after Y-3. | Tellurite resistance protein (tehA); Ion channel involved in potassium tellurite resistance. Belongs to the tellurite-resistance/dicarboxylate transporter (TDT) family. | 0.437 |
mtnN | hindIIM | HI_1216 | HI_0513 | Pfs protein (pfs); Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Belongs to the PNP/UDP phosphorylase family. MtnN subfamily. | Modification methylase (hindIIM); This methylase recognizes the double-stranded sequence GTYRAC, causes specific methylation on A-5 on both strands, and protects the DNA from cleavage by the HindII endonuclease; Belongs to the N(4)/N(6)-methyltransferase family. | 0.571 |
nadR | HI_0304 | HI_0763 | HI_0304 | Transcriptional regulator (nadR); This enzyme has two activities: nicotinamide mononucleotide (NMN) adenylyltransferase and ribosylnicotinamide (RN) kinase. The RN kinase activity catalyzes the phosphorylation of RN to form nicotinamide ribonucleotide. The NMN adenylyltransferase activity catalyzes the transfer of the AMP moiety of ATP to nicotinamide ribonucleotide to form NAD(+); In the C-terminal section; belongs to the bacterial RNK family. | Conserved hypothetical protein; Similar to PID:882477 SP:P52049 GB:U00096 PID:1789317 percent identity: 44.57; identified by sequence similarity; putative; Belongs to the UPF0301 (AlgH) family. | 0.936 |
nadR | hindIIM | HI_0763 | HI_0513 | Transcriptional regulator (nadR); This enzyme has two activities: nicotinamide mononucleotide (NMN) adenylyltransferase and ribosylnicotinamide (RN) kinase. The RN kinase activity catalyzes the phosphorylation of RN to form nicotinamide ribonucleotide. The NMN adenylyltransferase activity catalyzes the transfer of the AMP moiety of ATP to nicotinamide ribonucleotide to form NAD(+); In the C-terminal section; belongs to the bacterial RNK family. | Modification methylase (hindIIM); This methylase recognizes the double-stranded sequence GTYRAC, causes specific methylation on A-5 on both strands, and protects the DNA from cleavage by the HindII endonuclease; Belongs to the N(4)/N(6)-methyltransferase family. | 0.968 |
rpoC | hindIIM | HI_0514 | HI_0513 | DNA-directed RNA polymerase, beta' chain (rpoC); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | Modification methylase (hindIIM); This methylase recognizes the double-stranded sequence GTYRAC, causes specific methylation on A-5 on both strands, and protects the DNA from cleavage by the HindII endonuclease; Belongs to the N(4)/N(6)-methyltransferase family. | 0.602 |
rpoC | hindIIR | HI_0514 | HI_0512 | DNA-directed RNA polymerase, beta' chain (rpoC); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | Type II restriction endonuclease (HindIIR); Recognizes the double-stranded sequence GTYRAC and cleaves after Y-3. | 0.570 |
tehA | hindIIM | HI_0511 | HI_0513 | Tellurite resistance protein (tehA); Ion channel involved in potassium tellurite resistance. Belongs to the tellurite-resistance/dicarboxylate transporter (TDT) family. | Modification methylase (hindIIM); This methylase recognizes the double-stranded sequence GTYRAC, causes specific methylation on A-5 on both strands, and protects the DNA from cleavage by the HindII endonuclease; Belongs to the N(4)/N(6)-methyltransferase family. | 0.437 |
tehA | hindIIR | HI_0511 | HI_0512 | Tellurite resistance protein (tehA); Ion channel involved in potassium tellurite resistance. Belongs to the tellurite-resistance/dicarboxylate transporter (TDT) family. | Type II restriction endonuclease (HindIIR); Recognizes the double-stranded sequence GTYRAC and cleaves after Y-3. | 0.437 |