Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
HI_0519Transport protein, putative; Similar to GB:AE000511 PID:2314337 percent identity: 57.49; identified by sequence similarity; putative. (417 aa)    
Predicted Functional Partners:
hisD
Histidinol dehydrogenase (hisD); Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine.
 
      0.675
deoD
Purine-nucleoside phosphorylase (deoD); Similar to PID:1732037 percent identity: 88.19; identified by sequence similarity; putative.
       0.630
thyA
Thymidylate synthetase (thyA); Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
     
 0.539
HI_0520
Conserved hypothetical protein; Similar to GB:U14003 SP:P39409 PID:537219 GB:U00096 PID:1790839 percent identity: 36.27; identified by sequence similarity; putative.
       0.529
HI_0521
Conserved hypothetical protein; Similar to GB:U14003 SP:P37342 PID:537220 GB:U00096 PID:1790840 percent identity: 40.88; identified by sequence similarity; putative; To E.coli YjjI.
       0.529
Your Current Organism:
Haemophilus influenzae
NCBI taxonomy Id: 71421
Other names: H. influenzae Rd KW20, Haemophilus influenzae KW20, Haemophilus influenzae Rd, Haemophilus influenzae Rd KW20
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