Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
aspAAspartate ammonia-lyase (aspA); Similar to GB:U14003 SP:P04422 GB:L20944 GB:X02307 GB:X04066 percent identity: 77.85; identified by sequence similarity; putative; Belongs to the class-II fumarase/aspartase family. Aspartase subfamily. (475 aa)    
Predicted Functional Partners:
ansB
L-asparaginase II (ansB); Similar to GB:M34234 SP:P00805 GB:M34277 PID:145277 PID:146597 percent identity: 70.52; identified by sequence similarity; putative; Belongs to the asparaginase 1 family.
  
 
 0.980
pckA
Phosphoenolpyruvate carboxykinase (pckA); Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
   
 
 0.972
asnA
Aspartate--ammonia ligase (asnA); Similar to GB:L10328 SP:P00963 GB:J01657 GB:K00826 GB:M10679 percent identity: 63.33; identified by sequence similarity; putative.
     
  0.958
aspC
Aspartate aminotransferase (aspC); Similar to SP:P00509 GB:X03629 GB:X05904 PID:41011 PID:41013 percent identity: 62.63; identified by sequence similarity; putative; Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
     
  0.958
thrA
Aspartokinase I / homoserine dehydrogenase I (thrA); Similar to SP:P00561 GB:M10644 GB:V00360 GB:V00361 PID:147979 percent identity: 62.21; identified by sequence similarity; putative; In the C-terminal section; belongs to the homoserine dehydrogenase family.
    
 0.933
argG
Argininosuccinate synthetase (argG); Similar to GB:M35236 SP:P22767 PID:145342 PID:606111 GB:U00096 percent identity: 79.04; identified by sequence similarity; putative; Belongs to the argininosuccinate synthase family. Type 2 subfamily.
     
 0.925
purB
Adenylosuccinate lyase (purB); Similar to GB:M74924 SP:P25739 PID:145203 PID:42585 GB:U00096 percent identity: 76.97; identified by sequence similarity; putative.
     
 0.923
argH
Argininosuccinate lyase (argH); Similar to SP:P11447 GB:J01590 GB:M21446 PID:145335 PID:396307 percent identity: 73.52; identified by sequence similarity; putative.
     
 0.923
mdh
Malate dehydrogenase (mdh); Catalyzes the reversible oxidation of malate to oxaloacetate.
     
  0.920
HI_1632
Predicted coding region HI1632; Hypothetical protein; identified by GeneMark; putative; Belongs to the aspartokinase family.
     
  0.920
Your Current Organism:
Haemophilus influenzae
NCBI taxonomy Id: 71421
Other names: H. influenzae Rd KW20, Haemophilus influenzae KW20, Haemophilus influenzae Rd, Haemophilus influenzae Rd KW20
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