Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ureDUrease accessory protein (ureH); Required for maturation of urease via the functional incorporation of the urease nickel metallocenter. (261 aa)    
Predicted Functional Partners:
ureF
Urease accessory protein (ureF); Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
 
 
 0.995
ureG
Urease accessory protein (ureG); Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
 
 
 0.986
ureA
Urease, gamma subunit (ureA); Similar to SP:Q07399 PID:216360 percent identity: 67.00; identified by sequence similarity; putative; Belongs to the urease gamma subunit family.
 
 
 0.986
ureB
Urease, beta subunit (ureB); Similar to GB:L03307 SP:Q03283 PID:148153 percent identity: 61.76; identified by sequence similarity; putative; Belongs to the urease beta subunit family.
 
 
 0.984
ureE
Urease accessory protein (ureE); Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly. Belongs to the UreE family.
 
   
 0.967
ureC
Urease, alpha subunit (ureC); Similar to SP:Q07397 PID:216362 percent identity: 67.25; identified by sequence similarity; putative; Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
 
 
 0.962
aspA
Aspartate ammonia-lyase (aspA); Similar to GB:U14003 SP:P04422 GB:L20944 GB:X02307 GB:X04066 percent identity: 77.85; identified by sequence similarity; putative; Belongs to the class-II fumarase/aspartase family. Aspartase subfamily.
       0.458
Your Current Organism:
Haemophilus influenzae
NCBI taxonomy Id: 71421
Other names: H. influenzae Rd KW20, Haemophilus influenzae KW20, Haemophilus influenzae Rd, Haemophilus influenzae Rd KW20
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