| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| asnA | asnC | HI_0564 | HI_0563 | Aspartate--ammonia ligase (asnA); Similar to GB:L10328 SP:P00963 GB:J01657 GB:K00826 GB:M10679 percent identity: 63.33; identified by sequence similarity; putative. | Transcriptional regulatory protein (asnC); Activator of asnA transcription. | 0.529 |
| asnC | asnA | HI_0563 | HI_0564 | Transcriptional regulatory protein (asnC); Activator of asnA transcription. | Aspartate--ammonia ligase (asnA); Similar to GB:L10328 SP:P00963 GB:J01657 GB:K00826 GB:M10679 percent identity: 63.33; identified by sequence similarity; putative. | 0.529 |
| asnC | birA | HI_0563 | HI_0220.1 | Transcriptional regulatory protein (asnC); Activator of asnA transcription. | Biotin operon repressor/biotin acetyl coenzyme A carboxylase synthetase (birA); Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | 0.572 |
| asnC | bolA | HI_0563 | HI_0163 | Transcriptional regulatory protein (asnC); Activator of asnA transcription. | Transcriptional regulator, putative (bolA); Transcriptional regulator that plays an important role in general stress response. | 0.414 |
| asnC | fucR | HI_0563 | HI_0615 | Transcriptional regulatory protein (asnC); Activator of asnA transcription. | L-fucose operon activator (fucR); Transcriptional activator of the fuc operon. | 0.498 |
| asnC | metJ | HI_0563 | HI_0294 | Transcriptional regulatory protein (asnC); Activator of asnA transcription. | Met repressor (metJ); This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis; Belongs to the MetJ family. | 0.435 |
| asnC | xylR | HI_0563 | HI_1106 | Transcriptional regulatory protein (asnC); Activator of asnA transcription. | Xylose operon regluatory protein (xylR); Regulatory protein for the xylBAFGHR operon. | 0.492 |
| birA | asnC | HI_0220.1 | HI_0563 | Biotin operon repressor/biotin acetyl coenzyme A carboxylase synthetase (birA); Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | Transcriptional regulatory protein (asnC); Activator of asnA transcription. | 0.572 |
| birA | metJ | HI_0220.1 | HI_0294 | Biotin operon repressor/biotin acetyl coenzyme A carboxylase synthetase (birA); Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | Met repressor (metJ); This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis; Belongs to the MetJ family. | 0.419 |
| birA | xylR | HI_0220.1 | HI_1106 | Biotin operon repressor/biotin acetyl coenzyme A carboxylase synthetase (birA); Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | Xylose operon regluatory protein (xylR); Regulatory protein for the xylBAFGHR operon. | 0.760 |
| bolA | asnC | HI_0163 | HI_0563 | Transcriptional regulator, putative (bolA); Transcriptional regulator that plays an important role in general stress response. | Transcriptional regulatory protein (asnC); Activator of asnA transcription. | 0.414 |
| bolA | fucR | HI_0163 | HI_0615 | Transcriptional regulator, putative (bolA); Transcriptional regulator that plays an important role in general stress response. | L-fucose operon activator (fucR); Transcriptional activator of the fuc operon. | 0.446 |
| fucR | asnC | HI_0615 | HI_0563 | L-fucose operon activator (fucR); Transcriptional activator of the fuc operon. | Transcriptional regulatory protein (asnC); Activator of asnA transcription. | 0.498 |
| fucR | bolA | HI_0615 | HI_0163 | L-fucose operon activator (fucR); Transcriptional activator of the fuc operon. | Transcriptional regulator, putative (bolA); Transcriptional regulator that plays an important role in general stress response. | 0.446 |
| fucR | metJ | HI_0615 | HI_0294 | L-fucose operon activator (fucR); Transcriptional activator of the fuc operon. | Met repressor (metJ); This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis; Belongs to the MetJ family. | 0.470 |
| fucR | xylR | HI_0615 | HI_1106 | L-fucose operon activator (fucR); Transcriptional activator of the fuc operon. | Xylose operon regluatory protein (xylR); Regulatory protein for the xylBAFGHR operon. | 0.507 |
| metJ | asnC | HI_0294 | HI_0563 | Met repressor (metJ); This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis; Belongs to the MetJ family. | Transcriptional regulatory protein (asnC); Activator of asnA transcription. | 0.435 |
| metJ | birA | HI_0294 | HI_0220.1 | Met repressor (metJ); This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis; Belongs to the MetJ family. | Biotin operon repressor/biotin acetyl coenzyme A carboxylase synthetase (birA); Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | 0.419 |
| metJ | fucR | HI_0294 | HI_0615 | Met repressor (metJ); This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis; Belongs to the MetJ family. | L-fucose operon activator (fucR); Transcriptional activator of the fuc operon. | 0.470 |
| metJ | xylR | HI_0294 | HI_1106 | Met repressor (metJ); This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis; Belongs to the MetJ family. | Xylose operon regluatory protein (xylR); Regulatory protein for the xylBAFGHR operon. | 0.550 |