Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
HI_0570Conserved hypothetical protein; Similar to GB:U00096 PID:1790401 percent identity: 65.70; identified by sequence similarity; putative. (205 aa)    
Predicted Functional Partners:
oxyR
Hydrogen peroxide-inducible genes activator (oxyR); Required for the induction of a regulon of hydrogen peroxide inducible genes such as catalase and glutathione-reductase.
   
 
 0.842
fadR
Fatty acid metabolism regulator protein (fadR); Multifunctional regulator of fatty acid metabolism.
  
  
 0.800
plsB
Glycerol-3-phosphate acyltransferase (plsB); Similar to SP:P00482 GB:K00127 PID:147295 PID:148102 PID:148109 percent identity: 57.21; identified by sequence similarity; putative; Belongs to the GPAT/DAPAT family.
  
   
 0.770
rraB
Conserved hypothetical protein; Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome.
  
     0.730
metJ
Met repressor (metJ); This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis; Belongs to the MetJ family.
  
   
 0.726
seqA
seqA protein (seqA); Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated.
  
   
 0.710
HI_0028
Conserved hypothetical protein; Similar to GB:L07636 SP:P30977 PID:146621 GB:U00096 PID:1778548 percent identity: 50.59; identified by sequence similarity; putative; Belongs to the UPF0250 family.
  
     0.700
nlpI
Conserved hypothetical protein; May be involved in cell division.
  
     0.695
HI_1205
Conserved hypothetical protein; Similar to GB:U00096 PID:1788632 GB:U00096 PID:1788632 percent identity: 45.45; identified by sequence similarity; putative.
  
     0.653
yihI
Conserved hypothetical protein; A GTPase-activating protein (GAP) that modifies Der/EngA GTPase function. May play a role in ribosome biogenesis. Belongs to the YihI family.
  
     0.620
Your Current Organism:
Haemophilus influenzae
NCBI taxonomy Id: 71421
Other names: H. influenzae Rd KW20, Haemophilus influenzae KW20, Haemophilus influenzae Rd, Haemophilus influenzae Rd KW20
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