Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
fucIL-fucose isomerase (fucI); Converts the aldose L-fucose into the corresponding ketose L- fuculose. (604 aa)    
Predicted Functional Partners:
fucK
Fuculokinase (fucK); Catalyzes the phosphorylation of L-fuculose. Belongs to the FGGY kinase family.
 
 
 0.992
fucU
Fucose operon protein (fucU); Involved in the anomeric conversion of L-fucose.
 
  
 0.941
nagK
Sugar kinase, putative; Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P.
    
  0.893
fucP
L-fucose permease (fucP); Transport of L-fucose into the cell; Belongs to the major facilitator superfamily. FHS transporter (TC 2.A.1.7) family.
 
  
 0.732
fucA
L-fuculose phosphate aldolase (fucA); Involved in the degradation of L-fucose and D-arabinose. Catalyzes the reversible cleavage of L-fuculose 1-phosphate (Fuc1P) to yield dihydroxyacetone phosphate (DHAP) and L-lactaldehyde.
  
  
 0.547
nanE
Conserved hypothetical protein; Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N- acetylglucosamine-6-phosphate (GlcNAc-6-P).
  
   
 0.540
HI_1430
Short chain dehydrogenase/reductase; Similar to GB:U00096 PID:1787820 percent identity: 58.13; identified by sequence similarity; putative; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
     
  0.522
fucR
L-fucose operon activator (fucR); Transcriptional activator of the fuc operon.
     
 0.467
lyx
L-xylulose kinase (lyx); Similar to SP:P37677 PID:466718 GB:U00096 PID:1790005 percent identity: 53.93; identified by sequence similarity; putative; Belongs to the FGGY kinase family.
  
 
 0.446
xylB
Xylulose kinase; Catalyzes the phosphorylation of D-xylulose to D-xylulose 5- phosphate; Belongs to the FGGY kinase family.
  
 
 0.446
Your Current Organism:
Haemophilus influenzae
NCBI taxonomy Id: 71421
Other names: H. influenzae Rd KW20, Haemophilus influenzae KW20, Haemophilus influenzae Rd, Haemophilus influenzae Rd KW20
Server load: medium (50%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.