Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
trpStryptophanyl-tRNA synthetase (trpS); Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family. (334 aa)    
Predicted Functional Partners:
HI_0636
Conserved hypothetical protein; Similar to GB:U00096 PID:1788685 percent identity: 42.50; identified by sequence similarity; putative; Belongs to the UPF0381 family.
     
 0.828
gltX
glutamyl-tRNA synthetase (gltX); Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
 
 
 0.794
hflD
Conserved hypothetical protein; Similar to SP:P25746 PID:581207 GB:U00096 PID:1787377 percent identity: 51.21; identified by sequence similarity; putative.
     
 0.727
argS
arginyl-tRNA synthetase (argS); Similar to SP:P11875 GB:X15320 PID:581040 GB:U00096 PID:1736522 percent identity: 71.40; identified by sequence similarity; putative.
  
  
 0.705
metG
methionyl-tRNA synthetase (metG); Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
  
 
 0.697
pheT
phenylalanyl-tRNA synthetase, beta subunit (pheT); Similar to GB:K02844 SP:P07395 PID:146346 PID:43071 GB:U00096 percent identity: 65.28; identified by sequence similarity; putative; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
  
  
 0.696
serS
seryl-tRNA synthetase (serS); Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec).
  
 
 0.685
tyrR
Transcriptional regulatory protein (tyrR); Involved in transcriptional regulation of aromatic amino acid biosynthesis and transport.
      
 0.684
glnS
glutaminyl-tRNA synthetase (glnS); Similar to GB:V01575 SP:P00962 GB:J01617 GB:M10187 PID:146168 percent identity: 76.28; identified by sequence similarity; putative.
  
 
 0.671
trpC
Indole-3-glycerol phosphate synthase / phosphoribosylanthranilate isomerase (trpC); Bifunctional enzyme that catalyzes two sequential steps of tryptophan biosynthetic pathway. The first reaction is catalyzed by the isomerase, coded by the TrpF domain; the second reaction is catalyzed by the synthase, coded by the TrpC domain (By similarity).
  
  
 0.671
Your Current Organism:
Haemophilus influenzae
NCBI taxonomy Id: 71421
Other names: H. influenzae Rd KW20, Haemophilus influenzae KW20, Haemophilus influenzae Rd, Haemophilus influenzae Rd KW20
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