STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mdaBModulator of drug activity B (mdaB); NADPH-specific quinone reductase. (208 aa)    
Predicted Functional Partners:
kefBC
Glutathione-regulated potassium efflux system protein (kefC); Transport system that facilitate potassium-efflux, possibly by potassium-proton antiport; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.
  
 
 0.876
lysA
Diaminopimelate decarboxylase (lysA); Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine.
    
  0.606
alaA
Aminotransferase; Involved in the biosynthesis of alanine.
   
    0.592
emrB
Multidrug resistance protein B (emrB); Confers resistance to antibiotics; Belongs to the major facilitator superfamily. EmrB family.
   
  
 0.511
iga
Immunoglobin A1 protease (iga1); Virulence factor; cleaves host immunoglobulin A producing intact Fc and Fab fragments.
  
     0.460
rep
ATP-dependent DNA helicase (rep); Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction.
       0.426
HI_0650
Predicted coding region HI0650; Hypothetical protein; identified by GeneMark; putative.
       0.426
coaD
Lipopolysaccharide core biosynthesis protein (kdtB); Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family.
       0.426
waaA
3-deoxy-d-manno-octulosonic-acid transferase (kdtA); Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of a single 3-deoxy-D-manno-octulosonate (Kdo) residue from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'- bisphosphate precursor of lipid A. Is strictly monofunctional, i.e. is capable of adding only a single Kdo residue to the acceptor lipid. Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 30 subfamily.
       0.426
HI_0647
Transport protein, putative; Similar to GB:M57715 SP:P22037 PID:154179 percent identity: 42.40; identified by sequence similarity; putative.
       0.413
Your Current Organism:
Haemophilus influenzae
NCBI taxonomy Id: 71421
Other names: H. influenzae Rd KW20, Haemophilus influenzae KW20, Haemophilus influenzae Rd, Haemophilus influenzae Rd KW20
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