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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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glpKGlycerol kinase (glpK); Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. (503 aa)    
Predicted Functional Partners:
glpA
Anaerobic glycerol-3-phosphate dehydrogenase, subunit A (glpA); Similar to GB:M20938 SP:P13032 PID:146177 GB:U00096 PID:1788574 percent identity: 70.24; identified by sequence similarity; putative; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.
 0.988
glpF
Glycerol uptake facilitator protein (glpF); Glycerol enters the cell via the glycerol diffusion facilitator protein. This membrane protein facilitates the movement of glycerol across the cytoplasmic membrane (By similarity).
  
 
 0.975
plsY
Conserved hypothetical protein; Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
     
 0.941
glpQ
Glycerophosphoryl diester phosphodiesterase (glpQ); Glycerophosphoryl diester phosphodiesterase hydrolyzes deacylated phospholipids to G3P and the corresponding alcohols. Has a specific affinity for human immunoglobulin D myeloma protein.
  
  
 0.927
plsB
Glycerol-3-phosphate acyltransferase (plsB); Similar to SP:P00482 GB:K00127 PID:147295 PID:148102 PID:148109 percent identity: 57.21; identified by sequence similarity; putative; Belongs to the GPAT/DAPAT family.
     
 0.923
HI_1017
Glycerol uptake facilitator protein (glpF); Similar to GB:M99611 SP:P18156 PID:142991 PID:142997 PID:2226136 percent identity: 41.28; identified by sequence similarity; putative; Belongs to the MIP/aquaporin (TC 1.A.8) family.
  
 
 0.877
crr
PTS system, glucose-specific IIA component (crr); The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II complex composed of PtsG and Crr is involved in glucose transport.
    
 
 0.846
glpB
Anaerobic glycerol-3-phosphate dehydrogenase, subunit B (glpB); Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor (By similarity).
  
 
 0.781
glpC
Anaerobic glycerol-3-phosphate dehydrogenase, subunit C (glpC); Electron transfer protein; may also function as the membrane anchor for the GlpAB dimer.
  
 
 0.716
mazG
mazG protein (mazG); Involved in the regulation of bacterial cell survival under conditions of nutritional stress. Regulates the MazE-MazF toxin- antitoxin (TA) system that mediates programmed cell death (PCD). This is achieved by lowering the cellular concentration of (p)ppGpp produced by RelA under amino acid starvation, thus protecting the cell from the toxicity of MazF. Reduction of (p)ppGpp can be achieved by direct degradation of (p)ppGpp or by degradation of NTPs, which are substrates for (p)ppGpp synthesis by RelA (By similarity); Belongs to the nucleoside triphosphate pyrophos [...]
 
      0.651
Your Current Organism:
Haemophilus influenzae
NCBI taxonomy Id: 71421
Other names: H. influenzae Rd KW20, Haemophilus influenzae KW20, Haemophilus influenzae Rd, Haemophilus influenzae Rd KW20
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