| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| galE | galT | HI_0351 | HI_0820 | UDP-glucose 4-epimerase (galE); Involved in the metabolism of galactose. Catalyzes the conversion of UDP-galactose (UDP-Gal) to UDP-glucose (UDP-Glc) through a mechanism involving the transient reduction of NAD. By controlling the internal galactose concentration, it may be linked to the biosynthesis of lipopolysaccharide surface molecules, which are important for the pathogenesis of H.influenzae. | Galactose-1-phosphate uridylyltransferase (galT); Similar to SP:P31764 GB:X65934 PID:1573833 percent identity: 99.14; identified by sequence similarity; putative. | 0.997 |
| galE | galU | HI_0351 | HI_0812 | UDP-glucose 4-epimerase (galE); Involved in the metabolism of galactose. Catalyzes the conversion of UDP-galactose (UDP-Gal) to UDP-glucose (UDP-Glc) through a mechanism involving the transient reduction of NAD. By controlling the internal galactose concentration, it may be linked to the biosynthesis of lipopolysaccharide surface molecules, which are important for the pathogenesis of H.influenzae. | Glucosephosphate uridylyltransferase (galU); May play a role in stationary phase survival; Belongs to the UDPGP type 2 family. | 0.989 |
| galE | glmU | HI_0351 | HI_0642 | UDP-glucose 4-epimerase (galE); Involved in the metabolism of galactose. Catalyzes the conversion of UDP-galactose (UDP-Gal) to UDP-glucose (UDP-Glc) through a mechanism involving the transient reduction of NAD. By controlling the internal galactose concentration, it may be linked to the biosynthesis of lipopolysaccharide surface molecules, which are important for the pathogenesis of H.influenzae. | UDP-N-acetylglucosamine pyrophosphorylase (glmU); Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. In the C-terminal section; belongs to the transferase hexapeptide repeat family. | 0.953 |
| galE | murA | HI_0351 | HI_1081 | UDP-glucose 4-epimerase (galE); Involved in the metabolism of galactose. Catalyzes the conversion of UDP-galactose (UDP-Gal) to UDP-glucose (UDP-Glc) through a mechanism involving the transient reduction of NAD. By controlling the internal galactose concentration, it may be linked to the biosynthesis of lipopolysaccharide surface molecules, which are important for the pathogenesis of H.influenzae. | UDP-N-acetylglucosamine 1-carboxyvinyltransferase (murZ); Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | 0.436 |
| galT | galE | HI_0820 | HI_0351 | Galactose-1-phosphate uridylyltransferase (galT); Similar to SP:P31764 GB:X65934 PID:1573833 percent identity: 99.14; identified by sequence similarity; putative. | UDP-glucose 4-epimerase (galE); Involved in the metabolism of galactose. Catalyzes the conversion of UDP-galactose (UDP-Gal) to UDP-glucose (UDP-Glc) through a mechanism involving the transient reduction of NAD. By controlling the internal galactose concentration, it may be linked to the biosynthesis of lipopolysaccharide surface molecules, which are important for the pathogenesis of H.influenzae. | 0.997 |
| galT | galU | HI_0820 | HI_0812 | Galactose-1-phosphate uridylyltransferase (galT); Similar to SP:P31764 GB:X65934 PID:1573833 percent identity: 99.14; identified by sequence similarity; putative. | Glucosephosphate uridylyltransferase (galU); May play a role in stationary phase survival; Belongs to the UDPGP type 2 family. | 0.949 |
| galU | galE | HI_0812 | HI_0351 | Glucosephosphate uridylyltransferase (galU); May play a role in stationary phase survival; Belongs to the UDPGP type 2 family. | UDP-glucose 4-epimerase (galE); Involved in the metabolism of galactose. Catalyzes the conversion of UDP-galactose (UDP-Gal) to UDP-glucose (UDP-Glc) through a mechanism involving the transient reduction of NAD. By controlling the internal galactose concentration, it may be linked to the biosynthesis of lipopolysaccharide surface molecules, which are important for the pathogenesis of H.influenzae. | 0.989 |
| galU | galT | HI_0812 | HI_0820 | Glucosephosphate uridylyltransferase (galU); May play a role in stationary phase survival; Belongs to the UDPGP type 2 family. | Galactose-1-phosphate uridylyltransferase (galT); Similar to SP:P31764 GB:X65934 PID:1573833 percent identity: 99.14; identified by sequence similarity; putative. | 0.949 |
| galU | glgC | HI_0812 | HI_1359 | Glucosephosphate uridylyltransferase (galU); May play a role in stationary phase survival; Belongs to the UDPGP type 2 family. | Glucose-1-phosphate adenylyltransferase (glgC); Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family. | 0.942 |
| galU | glgP | HI_0812 | HI_1361 | Glucosephosphate uridylyltransferase (galU); May play a role in stationary phase survival; Belongs to the UDPGP type 2 family. | Glycogen phosphorylase (glgP); Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity). | 0.925 |
| galU | glgX | HI_0812 | HI_1358 | Glucosephosphate uridylyltransferase (galU); May play a role in stationary phase survival; Belongs to the UDPGP type 2 family. | Glycogen operon protein (glgX); Similar to GB:J01616 SP:P15067 PID:146135 PID:606366 GB:U00096 percent identity: 52.77; identified by sequence similarity; putative; Belongs to the glycosyl hydrolase 13 family. | 0.925 |
| galU | glmU | HI_0812 | HI_0642 | Glucosephosphate uridylyltransferase (galU); May play a role in stationary phase survival; Belongs to the UDPGP type 2 family. | UDP-N-acetylglucosamine pyrophosphorylase (glmU); Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. In the C-terminal section; belongs to the transferase hexapeptide repeat family. | 0.957 |
| galU | malQ | HI_0812 | HI_1356 | Glucosephosphate uridylyltransferase (galU); May play a role in stationary phase survival; Belongs to the UDPGP type 2 family. | 4-alpha-glucanotransferase (malQ); Similar to GB:M32793 SP:P15977 PID:146715 PID:606351 GB:U00096 percent identity: 41.59; identified by sequence similarity; putative; Belongs to the disproportionating enzyme family. | 0.923 |
| galU | murA | HI_0812 | HI_1081 | Glucosephosphate uridylyltransferase (galU); May play a role in stationary phase survival; Belongs to the UDPGP type 2 family. | UDP-N-acetylglucosamine 1-carboxyvinyltransferase (murZ); Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | 0.940 |
| galU | nanE | HI_0812 | HI_0145 | Glucosephosphate uridylyltransferase (galU); May play a role in stationary phase survival; Belongs to the UDPGP type 2 family. | Conserved hypothetical protein; Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N- acetylglucosamine-6-phosphate (GlcNAc-6-P). | 0.920 |
| galU | nanK | HI_0812 | HI_0144 | Glucosephosphate uridylyltransferase (galU); May play a role in stationary phase survival; Belongs to the UDPGP type 2 family. | Glucose kinase, putative; Catalyzes the phosphorylation of N-acetylmannosamine (ManNAc) to ManNAc-6-P; Belongs to the ROK (NagC/XylR) family. NanK subfamily. | 0.924 |
| glgC | galU | HI_1359 | HI_0812 | Glucose-1-phosphate adenylyltransferase (glgC); Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family. | Glucosephosphate uridylyltransferase (galU); May play a role in stationary phase survival; Belongs to the UDPGP type 2 family. | 0.942 |
| glgC | glgP | HI_1359 | HI_1361 | Glucose-1-phosphate adenylyltransferase (glgC); Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family. | Glycogen phosphorylase (glgP); Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity). | 0.997 |
| glgC | glgX | HI_1359 | HI_1358 | Glucose-1-phosphate adenylyltransferase (glgC); Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family. | Glycogen operon protein (glgX); Similar to GB:J01616 SP:P15067 PID:146135 PID:606366 GB:U00096 percent identity: 52.77; identified by sequence similarity; putative; Belongs to the glycosyl hydrolase 13 family. | 0.999 |
| glgC | malQ | HI_1359 | HI_1356 | Glucose-1-phosphate adenylyltransferase (glgC); Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family. | 4-alpha-glucanotransferase (malQ); Similar to GB:M32793 SP:P15977 PID:146715 PID:606351 GB:U00096 percent identity: 41.59; identified by sequence similarity; putative; Belongs to the disproportionating enzyme family. | 0.991 |