node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
HI_1698 | galE | HI_1698 | HI_0351 | Lipopolysaccharide biosynthesis protein; Similar to PID:633695 percent identity: 38.48; identified by sequence similarity; putative. | UDP-glucose 4-epimerase (galE); Involved in the metabolism of galactose. Catalyzes the conversion of UDP-galactose (UDP-Gal) to UDP-glucose (UDP-Glc) through a mechanism involving the transient reduction of NAD. By controlling the internal galactose concentration, it may be linked to the biosynthesis of lipopolysaccharide surface molecules, which are important for the pathogenesis of H.influenzae. | 0.765 |
HI_1698 | galT | HI_1698 | HI_0820 | Lipopolysaccharide biosynthesis protein; Similar to PID:633695 percent identity: 38.48; identified by sequence similarity; putative. | Galactose-1-phosphate uridylyltransferase (galT); Similar to SP:P31764 GB:X65934 PID:1573833 percent identity: 99.14; identified by sequence similarity; putative. | 0.569 |
HI_1698 | galU | HI_1698 | HI_0812 | Lipopolysaccharide biosynthesis protein; Similar to PID:633695 percent identity: 38.48; identified by sequence similarity; putative. | Glucosephosphate uridylyltransferase (galU); May play a role in stationary phase survival; Belongs to the UDPGP type 2 family. | 0.752 |
HI_1698 | glgA | HI_1698 | HI_1360 | Lipopolysaccharide biosynthesis protein; Similar to PID:633695 percent identity: 38.48; identified by sequence similarity; putative. | Glycogen synthase (glgA); Synthesizes alpha-1,4-glucan chains using ADP-glucose. | 0.653 |
HI_1698 | glgB | HI_1698 | HI_1357 | Lipopolysaccharide biosynthesis protein; Similar to PID:633695 percent identity: 38.48; identified by sequence similarity; putative. | 1,4-alpha-glucan branching enzyme (glgB); Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position; Belongs to the glycosyl hydrolase 13 family. GlgB subfamily. | 0.999 |
HI_1698 | glgC | HI_1698 | HI_1359 | Lipopolysaccharide biosynthesis protein; Similar to PID:633695 percent identity: 38.48; identified by sequence similarity; putative. | Glucose-1-phosphate adenylyltransferase (glgC); Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family. | 0.704 |
HI_1698 | rffG | HI_1698 | HI_0873 | Lipopolysaccharide biosynthesis protein; Similar to PID:633695 percent identity: 38.48; identified by sequence similarity; putative. | DTDP-glucose 4,6-dehydratase (rffG); Catalyzes the dehydration of dTDP-D-glucose to form dTDP-6- deoxy-D-xylo-4-hexulose via a three-step process involving oxidation, dehydration and reduction; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily. | 0.834 |
csrA | galU | HI_0813 | HI_0812 | Carbon storage regulator (csrA); A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s). | Glucosephosphate uridylyltransferase (galU); May play a role in stationary phase survival; Belongs to the UDPGP type 2 family. | 0.783 |
galE | HI_1698 | HI_0351 | HI_1698 | UDP-glucose 4-epimerase (galE); Involved in the metabolism of galactose. Catalyzes the conversion of UDP-galactose (UDP-Gal) to UDP-glucose (UDP-Glc) through a mechanism involving the transient reduction of NAD. By controlling the internal galactose concentration, it may be linked to the biosynthesis of lipopolysaccharide surface molecules, which are important for the pathogenesis of H.influenzae. | Lipopolysaccharide biosynthesis protein; Similar to PID:633695 percent identity: 38.48; identified by sequence similarity; putative. | 0.765 |
galE | galK | HI_0351 | HI_0819 | UDP-glucose 4-epimerase (galE); Involved in the metabolism of galactose. Catalyzes the conversion of UDP-galactose (UDP-Gal) to UDP-glucose (UDP-Glc) through a mechanism involving the transient reduction of NAD. By controlling the internal galactose concentration, it may be linked to the biosynthesis of lipopolysaccharide surface molecules, which are important for the pathogenesis of H.influenzae. | Galactokinase (galK); Catalyzes the transfer of the gamma-phosphate of ATP to D- galactose to form alpha-D-galactose-1-phosphate (Gal-1-P). Belongs to the GHMP kinase family. GalK subfamily. | 0.984 |
galE | galT | HI_0351 | HI_0820 | UDP-glucose 4-epimerase (galE); Involved in the metabolism of galactose. Catalyzes the conversion of UDP-galactose (UDP-Gal) to UDP-glucose (UDP-Glc) through a mechanism involving the transient reduction of NAD. By controlling the internal galactose concentration, it may be linked to the biosynthesis of lipopolysaccharide surface molecules, which are important for the pathogenesis of H.influenzae. | Galactose-1-phosphate uridylyltransferase (galT); Similar to SP:P31764 GB:X65934 PID:1573833 percent identity: 99.14; identified by sequence similarity; putative. | 0.983 |
galE | galU | HI_0351 | HI_0812 | UDP-glucose 4-epimerase (galE); Involved in the metabolism of galactose. Catalyzes the conversion of UDP-galactose (UDP-Gal) to UDP-glucose (UDP-Glc) through a mechanism involving the transient reduction of NAD. By controlling the internal galactose concentration, it may be linked to the biosynthesis of lipopolysaccharide surface molecules, which are important for the pathogenesis of H.influenzae. | Glucosephosphate uridylyltransferase (galU); May play a role in stationary phase survival; Belongs to the UDPGP type 2 family. | 0.903 |
galE | glmU | HI_0351 | HI_0642 | UDP-glucose 4-epimerase (galE); Involved in the metabolism of galactose. Catalyzes the conversion of UDP-galactose (UDP-Gal) to UDP-glucose (UDP-Glc) through a mechanism involving the transient reduction of NAD. By controlling the internal galactose concentration, it may be linked to the biosynthesis of lipopolysaccharide surface molecules, which are important for the pathogenesis of H.influenzae. | UDP-N-acetylglucosamine pyrophosphorylase (glmU); Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. In the C-terminal section; belongs to the transferase hexapeptide repeat family. | 0.568 |
galE | rffG | HI_0351 | HI_0873 | UDP-glucose 4-epimerase (galE); Involved in the metabolism of galactose. Catalyzes the conversion of UDP-galactose (UDP-Gal) to UDP-glucose (UDP-Glc) through a mechanism involving the transient reduction of NAD. By controlling the internal galactose concentration, it may be linked to the biosynthesis of lipopolysaccharide surface molecules, which are important for the pathogenesis of H.influenzae. | DTDP-glucose 4,6-dehydratase (rffG); Catalyzes the dehydration of dTDP-D-glucose to form dTDP-6- deoxy-D-xylo-4-hexulose via a three-step process involving oxidation, dehydration and reduction; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily. | 0.725 |
galK | galE | HI_0819 | HI_0351 | Galactokinase (galK); Catalyzes the transfer of the gamma-phosphate of ATP to D- galactose to form alpha-D-galactose-1-phosphate (Gal-1-P). Belongs to the GHMP kinase family. GalK subfamily. | UDP-glucose 4-epimerase (galE); Involved in the metabolism of galactose. Catalyzes the conversion of UDP-galactose (UDP-Gal) to UDP-glucose (UDP-Glc) through a mechanism involving the transient reduction of NAD. By controlling the internal galactose concentration, it may be linked to the biosynthesis of lipopolysaccharide surface molecules, which are important for the pathogenesis of H.influenzae. | 0.984 |
galK | galT | HI_0819 | HI_0820 | Galactokinase (galK); Catalyzes the transfer of the gamma-phosphate of ATP to D- galactose to form alpha-D-galactose-1-phosphate (Gal-1-P). Belongs to the GHMP kinase family. GalK subfamily. | Galactose-1-phosphate uridylyltransferase (galT); Similar to SP:P31764 GB:X65934 PID:1573833 percent identity: 99.14; identified by sequence similarity; putative. | 0.999 |
galK | galU | HI_0819 | HI_0812 | Galactokinase (galK); Catalyzes the transfer of the gamma-phosphate of ATP to D- galactose to form alpha-D-galactose-1-phosphate (Gal-1-P). Belongs to the GHMP kinase family. GalK subfamily. | Glucosephosphate uridylyltransferase (galU); May play a role in stationary phase survival; Belongs to the UDPGP type 2 family. | 0.772 |
galT | HI_1698 | HI_0820 | HI_1698 | Galactose-1-phosphate uridylyltransferase (galT); Similar to SP:P31764 GB:X65934 PID:1573833 percent identity: 99.14; identified by sequence similarity; putative. | Lipopolysaccharide biosynthesis protein; Similar to PID:633695 percent identity: 38.48; identified by sequence similarity; putative. | 0.569 |
galT | galE | HI_0820 | HI_0351 | Galactose-1-phosphate uridylyltransferase (galT); Similar to SP:P31764 GB:X65934 PID:1573833 percent identity: 99.14; identified by sequence similarity; putative. | UDP-glucose 4-epimerase (galE); Involved in the metabolism of galactose. Catalyzes the conversion of UDP-galactose (UDP-Gal) to UDP-glucose (UDP-Glc) through a mechanism involving the transient reduction of NAD. By controlling the internal galactose concentration, it may be linked to the biosynthesis of lipopolysaccharide surface molecules, which are important for the pathogenesis of H.influenzae. | 0.983 |
galT | galK | HI_0820 | HI_0819 | Galactose-1-phosphate uridylyltransferase (galT); Similar to SP:P31764 GB:X65934 PID:1573833 percent identity: 99.14; identified by sequence similarity; putative. | Galactokinase (galK); Catalyzes the transfer of the gamma-phosphate of ATP to D- galactose to form alpha-D-galactose-1-phosphate (Gal-1-P). Belongs to the GHMP kinase family. GalK subfamily. | 0.999 |