Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
HI_0828Conserved hypothetical protein; Similar to SP:P31070 percent identity: 67.35; identified by sequence similarity; putative. (98 aa)    
Predicted Functional Partners:
HI_0826
Conserved hypothetical transmembrane protein; Involved in cell division; probably involved in intracellular septation; Belongs to the YciB family.
  
    0.777
HI_0827
Conserved hypothetical; Similar to GB:K00431 SP:P04379 PID:455187 PID:902382 PID:902391 percent identity: 69.35; identified by sequence similarity; putative; Belongs to the acyl coenzyme A hydrolase family.
       0.774
slt
Soluble lytic murein transglycosylase, putative; Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division (By similarity).
       0.732
HI_0825
Predicted coding region HI0825; Hypothetical protein; identified by GeneMark; putative.
       0.727
trpR
Trp operon repressor (trpR); This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon and prevents the initiation of transcription (By similarity).
       0.615
lptA
Conserved hypothetical protein; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm.
  
     0.463
mglC
Galactoside ABC transporter, permease protein (mglC); Part of the binding-protein-dependent transport system for galactoside. Probably responsible for the translocation of the substrate across the membrane (By similarity).
       0.454
hflD
Conserved hypothetical protein; Similar to SP:P25746 PID:581207 GB:U00096 PID:1787377 percent identity: 51.21; identified by sequence similarity; putative.
  
    0.451
mglA
Galactoside ABC transporter, ATP-binding protein (mglA); Part of the ABC transporter complex MglABC involved in galactose/methyl galactoside import. Responsible for energy coupling to the transport system.
       0.431
mreD
Rod shape-determining protein (mreD); Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins (By similarity); Belongs to the MreD family.
  
     0.403
Your Current Organism:
Haemophilus influenzae
NCBI taxonomy Id: 71421
Other names: H. influenzae Rd KW20, Haemophilus influenzae KW20, Haemophilus influenzae Rd, Haemophilus influenzae Rd KW20
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