Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
HI_0839Conserved hypothetical protein; Similar to SP:P33920 PID:405914 GB:U00096 PID:1788513 percent identity: 52.38; identified by sequence similarity; putative. (341 aa)    
Predicted Functional Partners:
HI_0841
Conserved hypothetical protein; Similar to SP:P33922 PID:453987 GB:U00096 PID:1788515 percent identity: 41.57; identified by sequence similarity; putative; To E.coli YejM.
 
   
 0.881
HI_0840
Conserved hypothetical protein; Similar to SP:P33921 PID:405915 GB:U00096 PID:1788514 percent identity: 45.71; identified by sequence similarity; putative; Belongs to the UPF0352 family.
 
   
 0.791
bamE
Small protein A, putative; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.
  
    0.776
yihI
Conserved hypothetical protein; A GTPase-activating protein (GAP) that modifies Der/EngA GTPase function. May play a role in ribosome biogenesis. Belongs to the YihI family.
  
     0.731
sixA-A
Conserved hypothetical protein; Similar to GB:U00096 PID:1788681 percent identity: 40.26; identified by sequence similarity; putative; Belongs to the SixA phosphatase family.
  
     0.727
HI_1462.2
Conserved hypothetical protein; Similar to GB:U00096 PID:1788681 percent identity: 40.26; identified by sequence similarity; putative.
  
     0.727
HI_1205
Conserved hypothetical protein; Similar to GB:U00096 PID:1788632 GB:U00096 PID:1788632 percent identity: 45.45; identified by sequence similarity; putative.
  
     0.717
rraB
Conserved hypothetical protein; Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome.
  
   
 0.668
nlpI
Conserved hypothetical protein; May be involved in cell division.
  
     0.638
rseA
sigma-E factor negative regulatory protein (mclA); An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytopl [...]
  
     0.625
Your Current Organism:
Haemophilus influenzae
NCBI taxonomy Id: 71421
Other names: H. influenzae Rd KW20, Haemophilus influenzae KW20, Haemophilus influenzae Rd, Haemophilus influenzae Rd KW20
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