Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
HI_0862Conserved hypothetical protein; Involved in the import of queuosine (Q) precursors, required for Q precursor salvage; Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily. (235 aa)    
Predicted Functional Partners:
queF
Conserved hypothetical protein; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
  
  
 0.762
ppiB
Peptidyl-prolyl cis-trans isomerase B (ppiB); PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.
      0.722
HI_1680
Conserved hypothetical transmembrane protein; Similar to GB:U00096 PID:1787194 percent identity: 38.90; identified by sequence similarity; putative.
  
     0.669
grxA
Glutaredoxin (grx); Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins (By similarity).
  
    0.587
pdxH
Pyridoxamine phosphate oxidase (pdxH); Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
       0.530
tehB
Tellurite resistance protein (tehB); Probable S-adenosyl-L-methionine-dependent methyltransferase. Plays a role in both resistance to oxidative damage and heme uptake/utilization. Also protects H.influenzae from tellurite exposure in vitro; however, since H.influenzae grows only in humans, it is unlikely to encounter tellurite in its natural environment, and it is thus probable that tellurite resistance does not represent a biologically relevant role of TehB (By similarity); Belongs to the TehB family.
  
     0.477
rnr
Virulence-associated protein (vacB); 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
       0.449
thiB
Thiamin ABC transporter, periplasmic-binding protein (tbpA); Part of the ABC transporter complex ThiBPQ involved in thiamine import.
  
     0.428
Your Current Organism:
Haemophilus influenzae
NCBI taxonomy Id: 71421
Other names: H. influenzae Rd KW20, Haemophilus influenzae KW20, Haemophilus influenzae Rd, Haemophilus influenzae Rd KW20
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