Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
HI_0866Predicted coding region HI0866; Hypothetical protein; identified by GeneMark; putative. (207 aa)    
Predicted Functional Partners:
HI_1582
Conserved hypothetical protein; Similar to PID:1204257 SP:P52008 GB:U00096 PID:1788183 percent identity: 40.56; identified by sequence similarity; putative; To E.coli YecM.
  
     0.763
HI_0636
Conserved hypothetical protein; Similar to GB:U00096 PID:1788685 percent identity: 42.50; identified by sequence similarity; putative; Belongs to the UPF0381 family.
  
     0.748
arfA
Conserved hypothetical protein; Rescues ribosomes stalled at the 3' end of non-stop mRNAs. Recruits release factor 2 (RF2) to the stalled ribosome, helping position it correctly in the ribosomal A site so its GGQ motif can hydrolyze the peptidyl-tRNA bond (By similarity).
  
     0.747
HI_0045
Conserved hypothetical protein; Similar to GB:U14003 SP:P39187 PID:471102 PID:537057 GB:U00096 percent identity: 40.66; identified by sequence similarity; putative.
  
     0.743
HI_0974.1
Conserved hypothetical protein; Similar to SP:P45566 PID:606197 GB:U00096 PID:1789655 percent identity: 46.15; identified by sequence similarity; putative.
  
     0.718
holD
DNA polymerase III, psi subunit (holD); DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is unknown (By similarity).
  
     0.713
HI_0400
Conserved hypothetical protein; Similar to GB:U00096 PID:1788685 percent identity: 42.42; identified by sequence similarity; putative; Belongs to the UPF0381 family.
  
     0.713
HI_1724
Conserved hypothetical protein; Similar to SP:P45567 GB:U00096 PID:1786310 percent identity: 38.98; identified by sequence similarity; putative; Belongs to the UPF0231 family.
  
     0.698
HI_0869
Predicted coding region HI0869; Hypothetical protein; identified by GeneMark; putative.
     
 0.615
HI_0868
Conserved hypothetical protein; Similar to GB:AL009126 percent identity: 35.37; identified by sequence similarity; putative; Belongs to the glycosyltransferase 2 family.
     
 0.606
Your Current Organism:
Haemophilus influenzae
NCBI taxonomy Id: 71421
Other names: H. influenzae Rd KW20, Haemophilus influenzae KW20, Haemophilus influenzae Rd, Haemophilus influenzae Rd KW20
Server load: medium (44%) [HD]