Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
HI_0878Conserved hypothetical protein; Similar to SP:P28636 PID:216638 PID:606122 GB:U00096 PID:1789575 percent identity: 49.34; identified by sequence similarity; putative. (306 aa)    
Predicted Functional Partners:
obg
GTP-binding protein (yhbZ); An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
  
    0.818
rpmA
Ribosomal protein L27 (rpL27); Similar to GB:D13267 SP:P02427 PID:216637 PID:606123 GB:U00096 percent identity: 87.06; identified by sequence similarity; putative; Belongs to the bacterial ribosomal protein bL27 family.
       0.570
rplU
Ribosomal protein L21 (rpL21); This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.
       0.529
mtr
Tryptophan-specific transport protein (mtr); Involved in transporting tryptophan across the cytoplasmic membrane; Belongs to the amino acid/polyamine transporter 2 family. Mtr/TnaB/TyrP permease subfamily.
  
 
   0.527
tyrP-A
Tyrosine-specific transport protein (tyrP); Involved in transporting tyrosine across the cytoplasmic membrane; Belongs to the amino acid/polyamine transporter 2 family. Mtr/TnaB/TyrP permease subfamily.
  
 
   0.488
tyrP-B
Tyrosine-specific transport protein (tyrP); Involved in transporting tyrosine across the cytoplasmic membrane; Belongs to the amino acid/polyamine transporter 2 family. Mtr/TnaB/TyrP permease subfamily.
  
 
   0.480
tehB
Tellurite resistance protein (tehB); Probable S-adenosyl-L-methionine-dependent methyltransferase. Plays a role in both resistance to oxidative damage and heme uptake/utilization. Also protects H.influenzae from tellurite exposure in vitro; however, since H.influenzae grows only in humans, it is unlikely to encounter tellurite in its natural environment, and it is thus probable that tellurite resistance does not represent a biologically relevant role of TehB (By similarity); Belongs to the TehB family.
  
     0.432
Your Current Organism:
Haemophilus influenzae
NCBI taxonomy Id: 71421
Other names: H. influenzae Rd KW20, Haemophilus influenzae KW20, Haemophilus influenzae Rd, Haemophilus influenzae Rd KW20
Server load: low (38%) [HD]