| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| fusA | hrpA | HI_0579 | HI_1070 | Elongation factor G (fusA); Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity); Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. [...] | ATP-dependent helicase (hrpa); Similar to SP:P43329 PID:806328 GB:U00096 PID:1742299 PID:1742304 percent identity: 70.29; identified by sequence similarity; putative. | 0.752 |
| fusA | pnp | HI_0579 | HI_0229 | Elongation factor G (fusA); Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity); Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. [...] | Polynucleotide phosphorylase (pnp); Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. | 0.881 |
| fusA | rhlB | HI_0579 | HI_0892 | Elongation factor G (fusA); Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity); Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. [...] | ATP-dependent RNA helicase (rhlB); DEAD-box RNA helicase involved in RNA degradation. Has RNA- dependent ATPase activity and unwinds double-stranded RNA. Belongs to the DEAD box helicase family. RhlB subfamily. | 0.647 |
| fusA | rplC | HI_0579 | HI_0777 | Elongation factor G (fusA); Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity); Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. [...] | Ribosomal protein L3 (rpL3); One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | 0.994 |
| fusA | rplD | HI_0579 | HI_0778 | Elongation factor G (fusA); Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity); Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. [...] | Ribosomal protein L4 (rpL4); One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity). This protein when expressed in E.coli represses both transcription and translation of the endogenous S10 operon. As the H.influenzae S10 leader can be regulated in vitro by the E.coli L4 protein this strongly suggests the endogenous protein controls its own S10 operon in a sim [...] | 0.996 |
| fusA | rplM | HI_0579 | HI_1443 | Elongation factor G (fusA); Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity); Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. [...] | Ribosomal protein L13 (rpL13); This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.991 |
| hrpA | fusA | HI_1070 | HI_0579 | ATP-dependent helicase (hrpa); Similar to SP:P43329 PID:806328 GB:U00096 PID:1742299 PID:1742304 percent identity: 70.29; identified by sequence similarity; putative. | Elongation factor G (fusA); Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity); Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. [...] | 0.752 |
| hrpA | rhlB | HI_1070 | HI_0892 | ATP-dependent helicase (hrpa); Similar to SP:P43329 PID:806328 GB:U00096 PID:1742299 PID:1742304 percent identity: 70.29; identified by sequence similarity; putative. | ATP-dependent RNA helicase (rhlB); DEAD-box RNA helicase involved in RNA degradation. Has RNA- dependent ATPase activity and unwinds double-stranded RNA. Belongs to the DEAD box helicase family. RhlB subfamily. | 0.620 |
| hrpA | rplC | HI_1070 | HI_0777 | ATP-dependent helicase (hrpa); Similar to SP:P43329 PID:806328 GB:U00096 PID:1742299 PID:1742304 percent identity: 70.29; identified by sequence similarity; putative. | Ribosomal protein L3 (rpL3); One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | 0.701 |
| hrpA | rplD | HI_1070 | HI_0778 | ATP-dependent helicase (hrpa); Similar to SP:P43329 PID:806328 GB:U00096 PID:1742299 PID:1742304 percent identity: 70.29; identified by sequence similarity; putative. | Ribosomal protein L4 (rpL4); One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity). This protein when expressed in E.coli represses both transcription and translation of the endogenous S10 operon. As the H.influenzae S10 leader can be regulated in vitro by the E.coli L4 protein this strongly suggests the endogenous protein controls its own S10 operon in a sim [...] | 0.711 |
| hrpA | rplM | HI_1070 | HI_1443 | ATP-dependent helicase (hrpa); Similar to SP:P43329 PID:806328 GB:U00096 PID:1742299 PID:1742304 percent identity: 70.29; identified by sequence similarity; putative. | Ribosomal protein L13 (rpL13); This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.613 |
| hrpA | rsmB | HI_1070 | HI_0624 | ATP-dependent helicase (hrpa); Similar to SP:P43329 PID:806328 GB:U00096 PID:1742299 PID:1742304 percent identity: 70.29; identified by sequence similarity; putative. | Sun protein (sun); Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | 0.466 |
| pnp | fusA | HI_0229 | HI_0579 | Polynucleotide phosphorylase (pnp); Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. | Elongation factor G (fusA); Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity); Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. [...] | 0.881 |
| pnp | rhlB | HI_0229 | HI_0892 | Polynucleotide phosphorylase (pnp); Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. | ATP-dependent RNA helicase (rhlB); DEAD-box RNA helicase involved in RNA degradation. Has RNA- dependent ATPase activity and unwinds double-stranded RNA. Belongs to the DEAD box helicase family. RhlB subfamily. | 0.856 |
| pnp | rne | HI_0229 | HI_0413 | Polynucleotide phosphorylase (pnp); Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. | Ribonuclease E (rne); Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs. Belongs to the RNase E/G family. RNase E subfamily. | 0.940 |
| pnp | rplC | HI_0229 | HI_0777 | Polynucleotide phosphorylase (pnp); Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. | Ribosomal protein L3 (rpL3); One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | 0.824 |
| pnp | rplD | HI_0229 | HI_0778 | Polynucleotide phosphorylase (pnp); Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. | Ribosomal protein L4 (rpL4); One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity). This protein when expressed in E.coli represses both transcription and translation of the endogenous S10 operon. As the H.influenzae S10 leader can be regulated in vitro by the E.coli L4 protein this strongly suggests the endogenous protein controls its own S10 operon in a sim [...] | 0.833 |
| pnp | rplM | HI_0229 | HI_1443 | Polynucleotide phosphorylase (pnp); Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. | Ribosomal protein L13 (rpL13); This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.405 |
| pnp | rsmB | HI_0229 | HI_0624 | Polynucleotide phosphorylase (pnp); Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. | Sun protein (sun); Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | 0.437 |
| recQ | rhlB | HI_0728 | HI_0892 | ATP-dependent DNA helicase (recQ); DNA helicase; Belongs to the helicase family. RecQ subfamily. | ATP-dependent RNA helicase (rhlB); DEAD-box RNA helicase involved in RNA degradation. Has RNA- dependent ATPase activity and unwinds double-stranded RNA. Belongs to the DEAD box helicase family. RhlB subfamily. | 0.691 |
