Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
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[Homology]
Score
kefBCGlutathione-regulated potassium efflux system protein (kefC); Transport system that facilitate potassium-efflux, possibly by potassium-proton antiport; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. (618 aa)    
Predicted Functional Partners:
HI_1544
NAD(P)H oxidoreductase, putative; Similar to SP:Q64669 PID:595518 percent identity: 35.87; identified by sequence similarity; putative; Belongs to the NAD(P)H dehydrogenase (quinone) family.
 
 
 0.870
mdaB
Modulator of drug activity B (mdaB); NADPH-specific quinone reductase.
  
 
 0.847
trkA
TRK system potassium uptake protein (trkA); Part of a potassium transport system.
     
 0.633
mutT
Mutator mutT protein (mutT); Involved in the GO system responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine) from DNA and the nucleotide pool. 8-oxo-dGTP is inserted opposite dA and dC residues of template DNA with almost equal efficiency thus leading to A.T to G.C transversions. MutT specifically degrades 8-oxo-dGTP to the monophosphate (By similarity); Belongs to the Nudix hydrolase family.
  
    0.619
msrAB
Peptide methionine sulfoxide reductase (msrA); Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity).
     
 0.613
HI_0912
Predicted coding region HI0912; Hypothetical protein; identified by GeneMark; putative.
   
   0.607
thrA
Aspartokinase I / homoserine dehydrogenase I (thrA); Similar to SP:P00561 GB:M10644 GB:V00360 GB:V00361 PID:147979 percent identity: 62.21; identified by sequence similarity; putative; In the C-terminal section; belongs to the homoserine dehydrogenase family.
     
 0.605
nhaA
Na+/H+ antiporter (nhaA); Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons; Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
     
 0.592
gloB
Hydroxyacylglutathione hydrolase, putative; Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl- glutathione to form glutathione and D-lactic acid.
   
  
 0.552
rimK
Ribosomal protein S6 modification protein (rimK); Similar to SP:P17116 GB:X15859 PID:42747 GB:U00096 PID:1651386 percent identity: 45.55; identified by sequence similarity; putative.
  
  
 0.543
Your Current Organism:
Haemophilus influenzae
NCBI taxonomy Id: 71421
Other names: H. influenzae Rd KW20, Haemophilus influenzae KW20, Haemophilus influenzae Rd, Haemophilus influenzae Rd KW20
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