Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
HI_0952DNA repair protein (radC); Similar to GB:L10328 SP:P25531 GB:X63366 GB:X63367 PID:290488 percent identity: 49.77; identified by sequence similarity; putative; Belongs to the UPF0758 family. (234 aa)    
Predicted Functional Partners:
rec2
Recombination protein (rec2); Might contribute to transformation as a member of a membrane- bound pore complex at the base of the transformasome. It could directly interact with transforming DNA during translocation indirectly by participating in the assembly of the pore.
 
  
 0.686
mreC
Rod shape-determining protein (mreC); Involved in formation and maintenance of cell shape.
  
  
 0.682
coaBC
DNA/pantothenate metabolism flavoprotein (dfp); Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'- phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'- phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family.
       0.617
dut
Deoxyuridinetriphosphatase (dut); This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family.
     
 0.568
comF
Competence protein F (comF); Involved in transformation (competence for DNA uptake).
 
    0.541
slmA
Transcriptional regulator (ttk); Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions.
       0.539
rpmB
Ribosomal protein L28 (rpL28); Similar to GB:J01677 SP:P02428 PID:147708 PID:290487 GB:U00096 percent identity: 85.71; identified by sequence similarity; putative; Belongs to the bacterial ribosomal protein bL28 family.
       0.538
rpmG
Ribosomal protein L33 (rpL33); Similar to GB:J01677 SP:P02436 PID:147709 PID:290486 GB:U00096 percent identity: 81.48; identified by sequence similarity; putative; Belongs to the bacterial ribosomal protein bL33 family.
       0.534
dprA
DNA processing chain A (dprA); Essential for efficient chromosomal DNA transformation but not required for plasmid transformation. Its disruption can be partially complemented by the smf gene of E.coli ; Belongs to the DprA/Smf family.
  
  
 0.485
HI_0956
Conserved hypothetical protein; Similar to SP:P45536 PID:606288 GB:U00096 PID:1789753 percent identity: 50.70; identified by sequence similarity; putative; Belongs to the UPF0270 family.
       0.474
Your Current Organism:
Haemophilus influenzae
NCBI taxonomy Id: 71421
Other names: H. influenzae Rd KW20, Haemophilus influenzae KW20, Haemophilus influenzae Rd, Haemophilus influenzae Rd KW20
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