Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
prmARibosomal protein L11 methyltransferase (prmA); Methylates ribosomal protein L11; Belongs to the methyltransferase superfamily. PrmA family. (296 aa)    
Predicted Functional Partners:
rplK
Ribosomal protein L11 (rpL11); Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
    
 
 0.833
dnaJ
Heat shock protein (dnaJ); Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ [...]
  
  
 0.694
fis
Hin recombinational enhancer binding protein (fis); Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters; Belongs to the transcriptional regulatory Fis family.
  
  
 0.668
dusB
Nitrogen fixation protein (nifR3); Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the Dus family. DusB subfamily.
     
 0.657
HI_0976
Conserved hypothetical protein; Similar to GB:AL009126 percent identity: 25.21; identified by sequence similarity; putative.
       0.639
HI_0976.1
Conserved hypothetical protein; Similar to GB:AL009126 percent identity: 24.90; identified by sequence similarity; putative.
       0.639
HI_0977
Cell filamentation protein (fic); Probable adenylyltransferase that mediates the addition of adenosine 5'-monophosphate (AMP) to specific residues of target proteins.
       0.639
rsmE
Conserved hypothetical protein; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity).
  
  
 0.539
rlmH
Conserved hypothetical protein; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family.
 
  
 0.538
panF
Sodium/pantothenate symporter (panF); Catalyzes the sodium-dependent uptake of extracellular pantothenate; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
  
    0.536
Your Current Organism:
Haemophilus influenzae
NCBI taxonomy Id: 71421
Other names: H. influenzae Rd KW20, Haemophilus influenzae KW20, Haemophilus influenzae Rd, Haemophilus influenzae Rd KW20
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