Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
pfkA6-phosphofructokinase (pfkA); Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (321 aa)    
Predicted Functional Partners:
pgi
Glucose-6-phosphate isomerase (pgi); Similar to SP:P11537 GB:X15196 PID:396360 PID:42377 GB:U00096 percent identity: 77.05; identified by sequence similarity; putative.
  
 0.993
fba
Fructose-bisphosphate aldolase (fba); Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.
 
 
 0.988
fbp
Fructose-1,6-bisphosphatase (fbp); Similar to SP:P09200 GB:X12545 PID:41416 PID:537074 GB:U00096 percent identity: 70.48; identified by sequence similarity; putative.
    
 0.970
glpX
glpX protein (glpX); Catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate.
   
 
 0.965
fruK
1-phosphofructokinase (fruK); Similar to SP:P23539 GB:X53948 PID:405894 PID:41487 GB:U00096 percent identity: 55.41; identified by sequence similarity; putative; Belongs to the carbohydrate kinase PfkB family.
  
  
 0.944
tktA
Transketolase 1 (tktA); Catalyzes the reversible transfer of a two-carbon ketol group from sedoheptulose-7-phosphate to glyceraldehyde-3-phosphate, producing xylulose-5-phosphate and ribose-5-phosphate. Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate (By similarity).
  
 0.943
tal
Transaldolase B (talB); Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
   
 0.939
nagK
Sugar kinase, putative; Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P.
    
 0.926
HI_1710
Predicted coding region HI1710; Hypothetical protein; identified by GeneMark; putative.
     
 0.925
pykA
Pyruvate kinase, type II (pykA); Similar to GB:M63703 SP:P21599 GB:M87660 PID:147459 PID:146878 percent identity: 77.24; identified by sequence similarity; putative; Belongs to the pyruvate kinase family.
 
 
 0.912
Your Current Organism:
Haemophilus influenzae
NCBI taxonomy Id: 71421
Other names: H. influenzae Rd KW20, Haemophilus influenzae KW20, Haemophilus influenzae Rd, Haemophilus influenzae Rd KW20
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.