Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
Experiments
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[Homology]
Score
HI_1008Conserved hypothetical protein; Similar to GB:U00096 SP:P77415 PID:1580713 PID:1773126 PID:1786646 percent identity: 37.04; identified by sequence similarity; putative. (112 aa)    
Predicted Functional Partners:
rec2
Recombination protein (rec2); Might contribute to transformation as a member of a membrane- bound pore complex at the base of the transformasome. It could directly interact with transforming DNA during translocation indirectly by participating in the assembly of the pore.
 
  
 0.765
comE
Competence protein E (comE); Involved in transformation (competence for DNA uptake); Belongs to the bacterial secretin family. PilQ subfamily.
     
 0.639
hofD
Type 4 prepilin-like protein specific leader peptidase (hopD); Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue.
   
  
 0.567
hofC
Protein transport protein; Similar to GB:M32066 SP:P22609 PID:151066 percent identity: 29.18; identified by sequence similarity; putative.
  
  
 0.541
lspA
Lipoprotein signal peptidase (lspA); This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family.
     
 0.524
hofB
Protein transport protein; Similar to GB:M32066 SP:P22608 GB:S43866 PID:151065 percent identity: 41.16; identified by sequence similarity; putative; Belongs to the GSP E family.
  
  
 0.522
queF
Conserved hypothetical protein; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
 
   
 0.517
comM
Competence protein (comM); Induced during competence development. Not needed for DNA uptake. May be involved in a recombination step.
  
  
 0.494
HI_0938
Predicted coding region HI0938; Hypothetical protein; identified by GeneMark; putative.
   
  
 0.470
ispH
Penicillin tolerance protein (lytB); Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family.
       0.456
Your Current Organism:
Haemophilus influenzae
NCBI taxonomy Id: 71421
Other names: H. influenzae Rd KW20, Haemophilus influenzae KW20, Haemophilus influenzae Rd, Haemophilus influenzae Rd KW20
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