Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
HI_1009Glycerol-3-phosphate regulon repressor (glpR); Similar to SP:P09392 GB:M96795 PID:146186 PID:606358 GB:U00096 percent identity: 29.37; identified by sequence similarity; putative. (256 aa)    
Predicted Functional Partners:
fruA
PTS system, fructose-specific IIBC component (fruA); The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II FruAB PTS system is involved in fructose transport.
 
  
 0.792
fruK
1-phosphofructokinase (fruK); Similar to SP:P23539 GB:X53948 PID:405894 PID:41487 GB:U00096 percent identity: 55.41; identified by sequence similarity; putative; Belongs to the carbohydrate kinase PfkB family.
 
  
 0.693
otnK
Conserved hypothetical protein; Catalyzes the ATP-dependent phosphorylation of 3-oxo- tetronate to 3-oxo-tetronate 4-phosphate.
 
     0.598
otnI
Conserved hypothetical protein; Catalyzes the isomerization of 2-oxo-tetronate to 3-oxo- tetronate.
 
     0.578
ltnD
3-hydroxyisobutyrate dehydrogenase, putative; Catalyzes oxidation of L-threonate to 2-oxo-tetronate. Can use either NAD(+) or NADP(+) as cosubstrate, with a preference for NAD(+).
       0.519
otnC
Sugar isomerase, putative; Catalyzes the decarboxylation of 3-oxo-tetronate 4-phosphate to dihydroxyacetone phosphate (DHAP) and CO(2). Belongs to the aldolase class II family. AraD/FucA subfamily.
       0.519
denD
Conserved hypothetical protein; Catalyzes oxidation of D-erythronate to 2-oxo-tetronate. Can use either NAD(+) or NADP(+) as cosubstrate, with a preference for NAD(+).
       0.415
HI_1015
Gluconate permease (gntP); Similar to SP:P39835 PID:606350 GB:U00096 PID:1789820 percent identity: 32.35; identified by sequence similarity; putative.
       0.413
Your Current Organism:
Haemophilus influenzae
NCBI taxonomy Id: 71421
Other names: H. influenzae Rd KW20, Haemophilus influenzae KW20, Haemophilus influenzae Rd, Haemophilus influenzae Rd KW20
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