Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
HI_1017Glycerol uptake facilitator protein (glpF); Similar to GB:M99611 SP:P18156 PID:142991 PID:142997 PID:2226136 percent identity: 41.28; identified by sequence similarity; putative; Belongs to the MIP/aquaporin (TC 1.A.8) family. (213 aa)    
Predicted Functional Partners:
glpK
Glycerol kinase (glpK); Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family.
  
 
 0.877
glpQ
Glycerophosphoryl diester phosphodiesterase (glpQ); Glycerophosphoryl diester phosphodiesterase hydrolyzes deacylated phospholipids to G3P and the corresponding alcohols. Has a specific affinity for human immunoglobulin D myeloma protein.
  
 
 0.758
glpA
Anaerobic glycerol-3-phosphate dehydrogenase, subunit A (glpA); Similar to GB:M20938 SP:P13032 PID:146177 GB:U00096 PID:1788574 percent identity: 70.24; identified by sequence similarity; putative; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.
 
  
 0.751
ndk
Nucleoside diphosphate kinase (ndk); Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
   
 
 0.653
dnaJ
Heat shock protein (dnaJ); Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ [...]
    
 
 0.644
glpC
Anaerobic glycerol-3-phosphate dehydrogenase, subunit C (glpC); Electron transfer protein; may also function as the membrane anchor for the GlpAB dimer.
 
  
 0.614
ppiB
Peptidyl-prolyl cis-trans isomerase B (ppiB); PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.
    
   0.596
kdkA
Predicted coding region HI0260.1; Catalyzes the ATP-dependent phosphorylation of the 3-deoxy-D- manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position. To a lesser extent, can use GTP instead of ATP as substrate.
    
   0.539
fruA
PTS system, fructose-specific IIBC component (fruA); The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II FruAB PTS system is involved in fructose transport.
  
   
 0.531
HI_1015
Gluconate permease (gntP); Similar to SP:P39835 PID:606350 GB:U00096 PID:1789820 percent identity: 32.35; identified by sequence similarity; putative.
 
   
 0.476
Your Current Organism:
Haemophilus influenzae
NCBI taxonomy Id: 71421
Other names: H. influenzae Rd KW20, Haemophilus influenzae KW20, Haemophilus influenzae Rd, Haemophilus influenzae Rd KW20
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