Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Score
sgbHHexulose-6-phosphate synthase, putative; Catalyzes the decarboxylation of 3-keto-L-gulonate-6-P into L-xylulose-5-P; Belongs to the HPS/KGPDC family. KGPDC subfamily. (225 aa)    
Predicted Functional Partners:
sgbU
Hexulose-6-phosphate isomerase, putative; Catalyzes the isomerization of L-xylulose-5-phosphate to L- ribulose-5-phosphate.
 
 
 0.998
lyx
L-xylulose kinase (lyx); Similar to SP:P37677 PID:466718 GB:U00096 PID:1790005 percent identity: 53.93; identified by sequence similarity; putative; Belongs to the FGGY kinase family.
 
  
 0.952
sgbE
L-ribulose-5-phosphate 4-epimerase (araD); Catalyzes the interconversion of L-ribulose 5-phosphate (LRu5P) and D-xylulose 5-phosphate (D-Xu5P) via a retroaldol/aldol mechanism (carbon-carbon bond cleavage analogous to a class II aldolase reaction). May be involved in the utilization of 2,3-diketo-L-gulonate.
 
 
 0.944
HI_1678
kpsF protein (kpsF); Catalyzes the reversible aldol-ketol isomerization between D- ribulose 5-phosphate (Ru5P) and D-arabinose 5-phosphate (A5P). Belongs to the SIS family. GutQ/KpsF subfamily.
  
 
 0.911
tktA
Transketolase 1 (tktA); Catalyzes the reversible transfer of a two-carbon ketol group from sedoheptulose-7-phosphate to glyceraldehyde-3-phosphate, producing xylulose-5-phosphate and ribose-5-phosphate. Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate (By similarity).
    
 0.774
dlgD
Conserved hypothetical protein; Catalyzes the reduction of 2,3-diketo-L-gulonate in the presence of NADH, to form 3-keto-L-gulonate.
 
   
 0.758
HI_1032
Transcriptional regulator, putative; Similar to SP:P37671 PID:466712 GB:U00096 PID:1789999 percent identity: 63.74; identified by sequence similarity; putative.
     
 0.711
nanE
Conserved hypothetical protein; Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N- acetylglucosamine-6-phosphate (GlcNAc-6-P).
 
    0.620
xylB
Xylulose kinase; Catalyzes the phosphorylation of D-xylulose to D-xylulose 5- phosphate; Belongs to the FGGY kinase family.
    
  0.566
rpiA
Ribose 5-phosphate isomerase A (rpiA); Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
    
 0.551
Your Current Organism:
Haemophilus influenzae
NCBI taxonomy Id: 71421
Other names: H. influenzae Rd KW20, Haemophilus influenzae KW20, Haemophilus influenzae Rd, Haemophilus influenzae Rd KW20
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