Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
lyxL-xylulose kinase (lyx); Similar to SP:P37677 PID:466718 GB:U00096 PID:1790005 percent identity: 53.93; identified by sequence similarity; putative; Belongs to the FGGY kinase family. (485 aa)    
Predicted Functional Partners:
sgbH
Hexulose-6-phosphate synthase, putative; Catalyzes the decarboxylation of 3-keto-L-gulonate-6-P into L-xylulose-5-P; Belongs to the HPS/KGPDC family. KGPDC subfamily.
 
  
 0.952
dlgD
Conserved hypothetical protein; Catalyzes the reduction of 2,3-diketo-L-gulonate in the presence of NADH, to form 3-keto-L-gulonate.
 
  
 0.932
sgbE
L-ribulose-5-phosphate 4-epimerase (araD); Catalyzes the interconversion of L-ribulose 5-phosphate (LRu5P) and D-xylulose 5-phosphate (D-Xu5P) via a retroaldol/aldol mechanism (carbon-carbon bond cleavage analogous to a class II aldolase reaction). May be involved in the utilization of 2,3-diketo-L-gulonate.
 
 
 0.917
sgbU
Hexulose-6-phosphate isomerase, putative; Catalyzes the isomerization of L-xylulose-5-phosphate to L- ribulose-5-phosphate.
 
  
  0.913
xylA
Xylose isomerase (xylA); Similar to GB:X04691 SP:P00944 GB:K01996 GB:S68257 PID:148279 percent identity: 71.30; identified by sequence similarity; putative; Belongs to the xylose isomerase family.
 
 
 0.835
fucK
Fuculokinase (fucK); Catalyzes the phosphorylation of L-fuculose. Belongs to the FGGY kinase family.
  
  
0.679
rpe
Ribulose-phosphate 3-epimerase (dod); Catalyzes the reversible epimerization of D-ribulose 5- phosphate to D-xylulose 5-phosphate; Belongs to the ribulose-phosphate 3-epimerase family.
    
 0.650
HI_0053
Zinc-type alcohol dehydrogenase; Similar to GB:M96947 SP:Q06004 PID:304153 GB:AL009126 percent identity: 34.47; identified by sequence similarity; putative.
 
 
 0.609
HI_1028
Conserved hypothetical protein; Similar to SP:P37676 PID:466717 GB:U00096 PID:1790004 percent identity: 55.80; identified by sequence similarity; putative.
       0.598
HI_1030
Conserved hypothetical transmembrane protein; Similar to SP:P37674 PID:466715 GB:U00096 PID:1790002 percent identity: 37.50; identified by sequence similarity; putative.
  
    0.531
Your Current Organism:
Haemophilus influenzae
NCBI taxonomy Id: 71421
Other names: H. influenzae Rd KW20, Haemophilus influenzae KW20, Haemophilus influenzae Rd, Haemophilus influenzae Rd KW20
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