STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
HI_1052Transcriptional regulator, araC family, putative; Similar to SP:P35319 PID:581707 percent identity: 25.67; identified by sequence similarity; putative. (298 aa)    
Predicted Functional Partners:
HI_1051
ABC transporter, ATP-binding protein; Similar to GB:AL009126 percent identity: 33.76; identified by sequence similarity; putative.
 
    0.616
HI_1053
Conserved hypothetical protein; Similar to GB:M66060 SP:P27749 PID:141897 percent identity: 31.86; identified by sequence similarity; putative.
       0.540
xylR
Xylose operon regluatory protein (xylR); Regulatory protein for the xylBAFGHR operon.
 
 
 0.477
HI_1459
Sigma factor, putative; Similar to GB:AL009126 percent identity: 26.75; identified by sequence similarity; putative; Belongs to the sigma-70 factor family. ECF subfamily.
  
    0.446
rpoH
RNA polymerase sigma-32 factor (rpoH); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.
    
 
 0.410
rpoD
RNA polymerase sigma-70 factor (rpoD); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
    
 
 0.410
lexA
lexA repressor (lexA); Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
  
   0.408
Your Current Organism:
Haemophilus influenzae
NCBI taxonomy Id: 71421
Other names: H. influenzae Rd KW20, Haemophilus influenzae KW20, Haemophilus influenzae Rd, Haemophilus influenzae Rd KW20
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.