STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
nrfANitrite reductase, cytochrome C552 (nrfA); Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process; Belongs to the cytochrome c-552 family. (538 aa)    
Predicted Functional Partners:
napB
Periplasmic nitrate reductase (napB); Electron transfer subunit of the periplasmic nitrate reductase complex NapAB. Receives electrons from the membrane-anchored tetraheme c-type NapC protein and transfers these to NapA subunit, thus allowing electron flow between membrane and periplasm. Essential for periplasmic nitrate reduction with nitrate as the terminal electron acceptor; Belongs to the NapB family.
  
 
 0.978
nrfB
Nitrite reductase, cytochrome C-type protein (nrfB); Plays a role in nitrite reduction.
 
  
 0.974
nrfD
Nitrite reductase, transmembrane protein (nrfD); Probably involved in the transfer of electrons from the quinone pool to the type-c cytochromes; Belongs to the NrfD family.
 
  
 0.962
gdhA
Glutamate dehydrogenase (gdhA); Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia.
     
 0.925
glnA
Glutamine synthetase (glnA); Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia; Belongs to the glutamine synthetase family.
     
 0.921
nrfC
Nitrite reductase, Fe-S protein (nrfC); Probably involved in the transfer of electrons from the quinone pool to the type-c cytochromes.
 
 
 0.877
torY
Cytochrome C-type protein (yecK); Part of the anaerobic respiratory chain of trimethylamine-N- oxide reductase TorZ. Required for electron transfer to the TorZ terminal enzyme (By similarity).
 
 0.759
napC
Cytochrome C-type protein (napC); Mediates electron flow from quinones to the NapAB complex.
  
 0.727
ccmC
Heme exporter protein C (ccmC); Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmC/CycZ/HelC family.
     
 0.682
dmsA
Anaerobic dimethyl sulfoxide reductase, chain A (dmsA); Catalyzes the reduction of dimethyl sulfoxide (DMSO) to dimethyl sulfide (DMS). The terminal DMSO reductase can also use various sulfoxides and N-oxide compounds as terminal electron acceptor in addition to DMSO (By similarity); Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
  
 
 0.663
Your Current Organism:
Haemophilus influenzae
NCBI taxonomy Id: 71421
Other names: H. influenzae Rd KW20, Haemophilus influenzae KW20, Haemophilus influenzae Rd, Haemophilus influenzae Rd KW20
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