Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
HI_1163Conserved hypothetical protein; Similar to GB:U00096 SP:P77748 PID:1742760 PID:1787977 percent identity: 60.82; identified by sequence similarity; putative. (1027 aa)    
Predicted Functional Partners:
maeB
Malate oxidoreductase, putative; Similar to GB:U00096 PID:1788806 PID:1799885 PID:1799887 percent identity: 68.69; identified by sequence similarity; putative; In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
  
 
 0.970
pta
Phosphate acetyltransferase (pta); Involved in acetate metabolism; In the N-terminal section; belongs to the CobB/CobQ family.
  
 
 0.957
lldD
L-lactate dehydrogenase (lctD); Catalyzes the conversion of L-lactate to pyruvate. Is coupled to the respiratory chain; Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.
  
 0.906
HI_1218
L-lactate permease (lctP); May play a role in L-lactate transport; Belongs to the lactate permease family.
 
  
 0.822
frdB
Fumarate reductase, iron-sulfur protein (frdB); Similar to GB:U14003 SP:P00364 GB:J01611 PID:145264 PID:536997 percent identity: 75.51; identified by sequence similarity; putative.
   
 0.805
HI_1162
Conserved hypothetical protein; Similar to SP:P45736 GB:U00096 PID:1279405 PID:1787546 percent identity: 42.86; identified by sequence similarity; putative; To E.coli YcjD and H.influenzae HI_0925.
       0.773
serA
D-3-phosphoglycerate dehydrogenase (serA); Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L- serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.
 
  
 0.772
gph
Phosphoglycolate phosphatase (gph); Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress. Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.
    
 0.768
mdh
Malate dehydrogenase (mdh); Catalyzes the reversible oxidation of malate to oxaloacetate.
    
 0.764
glpA
Anaerobic glycerol-3-phosphate dehydrogenase, subunit A (glpA); Similar to GB:M20938 SP:P13032 PID:146177 GB:U00096 PID:1788574 percent identity: 70.24; identified by sequence similarity; putative; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.
  
 
 0.757
Your Current Organism:
Haemophilus influenzae
NCBI taxonomy Id: 71421
Other names: H. influenzae Rd KW20, Haemophilus influenzae KW20, Haemophilus influenzae Rd, Haemophilus influenzae Rd KW20
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