Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
sprTSprt protein (sprT); Similar to SP:P39902 PID:1208420 PID:882473 GB:U00096 PID:1789313 percent identity: 46.00; identified by sequence similarity; putative; Belongs to the SprT family. (156 aa)    
Predicted Functional Partners:
tusC
Conserved hypothetical protein; Could be part of a sulfur-relay system; Belongs to the DsrF/TusC family.
  
     0.561
HI_0589
Sigma factor regulatory protein, putative; Similar to SP:P46187 PID:987645 PID:1045631 PID:1050877 GB:U00096 percent identity: 29.01; identified by sequence similarity; putative.
  
     0.536
metK
S-adenosylmethionine synthetase (metX); Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
       0.503
lapA
Conserved hypothetical protein; Involved in the assembly of lipopolysaccharide (LPS). Belongs to the LapA family.
  
     0.498
HI_0839
Conserved hypothetical protein; Similar to SP:P33920 PID:405914 GB:U00096 PID:1788513 percent identity: 52.38; identified by sequence similarity; putative.
  
     0.485
opa
Opacity protein, putative; Similar to GB:X15780 PID:1333789 percent identity: 38.76; identified by sequence similarity; putative; Belongs to the opacity porin family.
     
 0.478
yacG
Conserved hypothetical protein; Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C- terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.
  
     0.451
pmbA
pmbA protein (pmbA); Probable metalloprotease; Belongs to the peptidase U62 family.
  
   
 0.421
mreD
Rod shape-determining protein (mreD); Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins (By similarity); Belongs to the MreD family.
  
     0.408
Your Current Organism:
Haemophilus influenzae
NCBI taxonomy Id: 71421
Other names: H. influenzae Rd KW20, Haemophilus influenzae KW20, Haemophilus influenzae Rd, Haemophilus influenzae Rd KW20
Server load: low (38%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.