Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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bcrBicyclomycin resistance protein (bcr); Involved in sulfonamide (sulfathiazole) and bicyclomycin resistance. Probable membrane translocase (By similarity). Belongs to the major facilitator superfamily. Bcr/CmlA family. (398 aa)    
Predicted Functional Partners:
rsuA
16s pseudouridylate 516 synthase (rsuA); Responsible for synthesis of pseudouridine from uracil-516 in 16S ribosomal RNA; Belongs to the pseudouridine synthase RsuA family.
       0.811
menC
O-succinylbenzoate-CoA synthase (menC); Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB).
      
 0.580
HI_1244
Predicted coding region HI1244; Hypothetical protein; identified by GeneMark; putative.
       0.541
emrA
Multidrug resistance protein A (emrA); Confers resistance to antibiotics; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
   
 
 0.479
hsrA
Conserved hypothetical transmembrane protein; Similar to GB:L10328 SP:P31474 PID:290604 GB:U00096 PID:1790195 percent identity: 44.91; identified by sequence similarity; putative.
  
   
 0.446
emrB
Multidrug resistance protein B (emrB); Confers resistance to antibiotics; Belongs to the major facilitator superfamily. EmrB family.
  
   
 0.416
pheA
Chorismate mutase / prephenate dehydratase (pheA); Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.
  
 
  0.416
Your Current Organism:
Haemophilus influenzae
NCBI taxonomy Id: 71421
Other names: H. influenzae Rd KW20, Haemophilus influenzae KW20, Haemophilus influenzae Rd, Haemophilus influenzae Rd KW20
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