| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| HI_1253 | ettA | HI_1253 | HI_1252 | Conserved hypothetical protein; Similar to PID:968932 GB:U00096 PID:1787464 percent identity: 31.73; identified by sequence similarity; putative. | ABC transporter, ATP-binding protein; A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase; Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily. | 0.714 |
| HI_1253 | tmcA | HI_1253 | HI_1254 | Conserved hypothetical protein; Similar to PID:968932 GB:U00096 PID:1787464 percent identity: 31.73; identified by sequence similarity; putative. | Conserved hypothetical protein; Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP). | 0.773 |
| ettA | HI_1253 | HI_1252 | HI_1253 | ABC transporter, ATP-binding protein; A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase; Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily. | Conserved hypothetical protein; Similar to PID:968932 GB:U00096 PID:1787464 percent identity: 31.73; identified by sequence similarity; putative. | 0.714 |
| ettA | rplC | HI_1252 | HI_0777 | ABC transporter, ATP-binding protein; A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase; Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily. | Ribosomal protein L3 (rpL3); One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | 0.630 |
| ettA | rplD | HI_1252 | HI_0778 | ABC transporter, ATP-binding protein; A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase; Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily. | Ribosomal protein L4 (rpL4); One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity). This protein when expressed in E.coli represses both transcription and translation of the endogenous S10 operon. As the H.influenzae S10 leader can be regulated in vitro by the E.coli L4 protein this strongly suggests the endogenous protein controls its own S10 operon in a sim [...] | 0.634 |
| ettA | rplT | HI_1252 | HI_1320 | ABC transporter, ATP-binding protein; A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase; Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily. | Ribosomal protein L20 (rpL20); Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity). | 0.638 |
| ettA | rplU | HI_1252 | HI_0880 | ABC transporter, ATP-binding protein; A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase; Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily. | Ribosomal protein L21 (rpL21); This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. | 0.650 |
| ettA | rpmD | HI_1252 | HI_0796 | ABC transporter, ATP-binding protein; A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase; Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily. | Ribosomal protein L30 (rpL30); Similar to GB:X01563 SP:P02430 GB:M24532 PID:42987 PID:606236 percent identity: 79.66; identified by sequence similarity; putative. | 0.634 |
| ettA | rpmH | HI_1252 | HI_0998 | ABC transporter, ATP-binding protein; A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase; Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily. | Ribosomal protein L34 (rpL34); Similar to GB:L10328 SP:P02437 GB:J01602 GB:M11056 PID:145759 percent identity: 86.36; identified by sequence similarity; putative; Belongs to the bacterial ribosomal protein bL34 family. | 0.633 |
| ettA | rpsC | HI_1252 | HI_0783 | ABC transporter, ATP-binding protein; A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase; Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily. | Ribosomal protein S3 (rpS3); Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family. | 0.637 |
| ettA | rpsJ | HI_1252 | HI_0776 | ABC transporter, ATP-binding protein; A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase; Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily. | Ribosomal protein S10 (rpS10); Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family. | 0.629 |
| ettA | tmcA | HI_1252 | HI_1254 | ABC transporter, ATP-binding protein; A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase; Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily. | Conserved hypothetical protein; Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP). | 0.751 |
| rplC | ettA | HI_0777 | HI_1252 | Ribosomal protein L3 (rpL3); One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | ABC transporter, ATP-binding protein; A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase; Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily. | 0.630 |
| rplC | rplD | HI_0777 | HI_0778 | Ribosomal protein L3 (rpL3); One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | Ribosomal protein L4 (rpL4); One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity). This protein when expressed in E.coli represses both transcription and translation of the endogenous S10 operon. As the H.influenzae S10 leader can be regulated in vitro by the E.coli L4 protein this strongly suggests the endogenous protein controls its own S10 operon in a sim [...] | 0.999 |
| rplC | rplT | HI_0777 | HI_1320 | Ribosomal protein L3 (rpL3); One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | Ribosomal protein L20 (rpL20); Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity). | 0.994 |
| rplC | rplU | HI_0777 | HI_0880 | Ribosomal protein L3 (rpL3); One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | Ribosomal protein L21 (rpL21); This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. | 0.994 |
| rplC | rpmD | HI_0777 | HI_0796 | Ribosomal protein L3 (rpL3); One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | Ribosomal protein L30 (rpL30); Similar to GB:X01563 SP:P02430 GB:M24532 PID:42987 PID:606236 percent identity: 79.66; identified by sequence similarity; putative. | 0.998 |
| rplC | rpmH | HI_0777 | HI_0998 | Ribosomal protein L3 (rpL3); One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | Ribosomal protein L34 (rpL34); Similar to GB:L10328 SP:P02437 GB:J01602 GB:M11056 PID:145759 percent identity: 86.36; identified by sequence similarity; putative; Belongs to the bacterial ribosomal protein bL34 family. | 0.956 |
| rplC | rpsC | HI_0777 | HI_0783 | Ribosomal protein L3 (rpL3); One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | Ribosomal protein S3 (rpS3); Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family. | 0.999 |
| rplC | rpsJ | HI_0777 | HI_0776 | Ribosomal protein L3 (rpL3); One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | Ribosomal protein S10 (rpS10); Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family. | 0.999 |
