STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gloBHydroxyacylglutathione hydrolase, putative; Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl- glutathione to form glutathione and D-lactic acid. (238 aa)    
Predicted Functional Partners:
gloA
Lactoylglutathione lyase (gloA); Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.
 
  
 0.964
HI_1163
Conserved hypothetical protein; Similar to GB:U00096 SP:P77748 PID:1742760 PID:1787977 percent identity: 60.82; identified by sequence similarity; putative.
    
 0.720
grxD
Conserved hypothetical protein; Monothiol glutaredoxin involved in the biogenesis of iron- sulfur clusters.
  
  
 0.710
gloC
Conserved hypothetical protein; Type II glyoxalase, isozyme of GloB, that hydrolyzes (R)-S- lactoylglutathione to (R)-lactate and glutathione. Plays a role in methylglyoxal (MG) detoxification.
  
  
 
0.646
HI_1273
Conserved hypothetical protein; Similar to PID:1816658 percent identity: 37.25; identified by sequence similarity; putative.
       0.620
HI_1272
ABC transporter, ATP-binding protein; Similar to GB:AE000511 SP:O05732 PID:2072456 PID:2314024 percent identity: 34.43; identified by sequence similarity; putative; Belongs to the ABC transporter superfamily.
  
    0.612
glpE
glpE protein (glpE); Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide.
  
 0.568
HI_0744
Conserved hypothetical protein; Similar to SP:P37688 PID:466749 GB:U00096 PID:1790040 percent identity: 50.74; identified by sequence similarity; putative.
  
 0.568
ddh
D-lactate dehydrogenase, fermentative (ldhA); Similar to PID:1049265 SP:P52643 GB:U00096 PID:1742253 PID:1742259 percent identity: 70.86; identified by sequence similarity; putative; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
   
 
  0.565
acpP
Acyl carrier protein (acpP); Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family.
    
 
 0.560
Your Current Organism:
Haemophilus influenzae
NCBI taxonomy Id: 71421
Other names: H. influenzae Rd KW20, Haemophilus influenzae KW20, Haemophilus influenzae Rd, Haemophilus influenzae Rd KW20
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.